Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy

Thuss Sanguansak, Prapapan Pitujaturont, Yosanan Yospaiboon, Suthasinee Sinawat, Tanapat Ratanapakorn, Chavakij Bhoomibunchoo Department of Ophthalmology, Faculty of Medicine, KKU Eye Center, Khon Kaen University, Khon Kaen, Thailand Objective: To study the macular sensitivity after half-dose vert...

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Autores principales:	Sanguansak T, Pitujaturont P, Yospaiboon Y, Sinawat S, Ratanapakorn T, Bhoomibunchoo C
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/c492592c3015478fa53674f0f38cdb8d
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spelling	oai:doaj.org-article:c492592c3015478fa53674f0f38cdb8d2021-12-02T07:08:06ZMacular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy1177-5483https://doaj.org/article/c492592c3015478fa53674f0f38cdb8d2015-12-01T00:00:00Zhttps://www.dovepress.com/macular-sensitivity-after-half-dose-verteporfin-photodynamic-therapy-i-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Thuss Sanguansak, Prapapan Pitujaturont, Yosanan Yospaiboon, Suthasinee Sinawat, Tanapat Ratanapakorn, Chavakij Bhoomibunchoo Department of Ophthalmology, Faculty of Medicine, KKU Eye Center, Khon Kaen University, Khon Kaen, Thailand Objective: To study the macular sensitivity after half-dose verteporfin photodynamic therapy in patients with resolved central serous chorioretinopathy using the automated static perimeter.Methods: Prospective consecutive case study of 24 patients with resolved central serous chorioretinopathy was performed. The macular sensitivity was measured using a conventional automated static perimeter with the Swedish interactive threshold algorithm 10-2 and foveal threshold. Best corrected visual acuity, intraocular pressure, fundus examination, macular thickness, and volume were also examined. The mean macular sensitivities of the affected eyes and their normal fellow eyes were calculated and compared. P<0.05 was considered statistically significant.Results: The mean macular sensitivities of the affected eyes were lower than the normal fellow eyes with a statistically significant difference in all areas of the study (P<0.05). Best corrected visual acuity improved significantly from pretreatment (0.26±0.3 logMAR) to posttreatment (0.075±0.15 logMAR, P<0.05). Macular thicknesses in affected eyes were 230.66±67.34 µm and in the normal eyes were 238.33±92.26 µm (P=0.68). Macular volumes in affected eyes were 8.77±0.49 and in the normal eyes were 8.70±0.50 (P=0.60). These findings were not statistically significant.Conclusion: Eyes with resolved central serous chorioretinopathy after half-dose verteporfin photodynamic therapy had lower macular sensitivity than normal fellow eyes. These findings agreed well with the previous microperimetric studies. The conventional automated static perimeter can also be used when a microperimeter is not available. Keywords: macular sensitivity, half-dose photodynamic therapy, automated static perimeter, central serous chorioretinopathySanguansak TPitujaturont PYospaiboon YSinawat SRatanapakorn TBhoomibunchoo CDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 2257-2261 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Sanguansak T Pitujaturont P Yospaiboon Y Sinawat S Ratanapakorn T Bhoomibunchoo C Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy
description	Thuss Sanguansak, Prapapan Pitujaturont, Yosanan Yospaiboon, Suthasinee Sinawat, Tanapat Ratanapakorn, Chavakij Bhoomibunchoo Department of Ophthalmology, Faculty of Medicine, KKU Eye Center, Khon Kaen University, Khon Kaen, Thailand Objective: To study the macular sensitivity after half-dose verteporfin photodynamic therapy in patients with resolved central serous chorioretinopathy using the automated static perimeter.Methods: Prospective consecutive case study of 24 patients with resolved central serous chorioretinopathy was performed. The macular sensitivity was measured using a conventional automated static perimeter with the Swedish interactive threshold algorithm 10-2 and foveal threshold. Best corrected visual acuity, intraocular pressure, fundus examination, macular thickness, and volume were also examined. The mean macular sensitivities of the affected eyes and their normal fellow eyes were calculated and compared. P<0.05 was considered statistically significant.Results: The mean macular sensitivities of the affected eyes were lower than the normal fellow eyes with a statistically significant difference in all areas of the study (P<0.05). Best corrected visual acuity improved significantly from pretreatment (0.26±0.3 logMAR) to posttreatment (0.075±0.15 logMAR, P<0.05). Macular thicknesses in affected eyes were 230.66±67.34 µm and in the normal eyes were 238.33±92.26 µm (P=0.68). Macular volumes in affected eyes were 8.77±0.49 and in the normal eyes were 8.70±0.50 (P=0.60). These findings were not statistically significant.Conclusion: Eyes with resolved central serous chorioretinopathy after half-dose verteporfin photodynamic therapy had lower macular sensitivity than normal fellow eyes. These findings agreed well with the previous microperimetric studies. The conventional automated static perimeter can also be used when a microperimeter is not available. Keywords: macular sensitivity, half-dose photodynamic therapy, automated static perimeter, central serous chorioretinopathy
format	article
author	Sanguansak T Pitujaturont P Yospaiboon Y Sinawat S Ratanapakorn T Bhoomibunchoo C
author_facet	Sanguansak T Pitujaturont P Yospaiboon Y Sinawat S Ratanapakorn T Bhoomibunchoo C
author_sort	Sanguansak T
title	Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy
title_short	Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy
title_full	Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy
title_fullStr	Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy
title_full_unstemmed	Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy
title_sort	macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/c492592c3015478fa53674f0f38cdb8d
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Macular sensitivity after half-dose verteporfin photodynamic therapy in central serous chorioretinopathy

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