Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery

The bacterial pathogen Shigella flexneri causes bacillary dysentery (bloody diarrhoea). Here, Yum et al. present an infant rabbit model of S. flexneri infection that recapitulates human disease symptoms and features bacterial dissemination as an essential determinant of pathogenesis.

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Auteurs principaux: Lauren K. Yum, Mariana X. Byndloss, Sanford H. Feldman, Hervé Agaisse
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/c499ad32f62d4286a31b88f1da55b0bd
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Résumé:The bacterial pathogen Shigella flexneri causes bacillary dysentery (bloody diarrhoea). Here, Yum et al. present an infant rabbit model of S. flexneri infection that recapitulates human disease symptoms and features bacterial dissemination as an essential determinant of pathogenesis.