A Combination of Anti-PD-L1 Treatment and Therapeutic Vaccination Facilitates Improved Retroviral Clearance via Reactivation of Highly Exhausted T Cells
Despite significant efforts, vaccines are not yet available for every infectious pathogen, and the search for a protective approach to prevent the establishment of chronic infections, i.e., with HIV, continues. Immune checkpoint therapies targeting inhibitory receptors, such as PD-1, have shown imp...
Guardado en:
Autores principales: | Torben Knuschke, Sebastian Kollenda, Christina Wenzek, Gennadiy Zelinskyy, Philine Steinbach, Ulf Dittmer, Jan Buer, Matthias Epple, Astrid M. Westendorf |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c4b0311ffd9843a69b3db45c416f2a05 |
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