SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus
Chen et al. find that SARS-CoV-2 encoded proteins and some anti-COVID-19 drugs can induce lytic reactivation of Kaposi’s sarcoma-associated herpesvirus (KSHV), one of the major human oncogenic viruses. This study suggests that KSHV-positive patients exposed to COVID-19 or undergoing its treatment ma...
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Nature Portfolio
2021
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oai:doaj.org-article:c4ba9901e2664db29bea3935dc8d15472021-12-02T17:51:20ZSARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus10.1038/s42003-021-02220-z2399-3642https://doaj.org/article/c4ba9901e2664db29bea3935dc8d15472021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02220-zhttps://doaj.org/toc/2399-3642Chen et al. find that SARS-CoV-2 encoded proteins and some anti-COVID-19 drugs can induce lytic reactivation of Kaposi’s sarcoma-associated herpesvirus (KSHV), one of the major human oncogenic viruses. This study suggests that KSHV-positive patients exposed to COVID-19 or undergoing its treatment may have increased risks to develop virus-associated cancers, even after they have fully recovered from COVID-19.Jungang ChenLu DaiLindsey BarrettJennifer JamesKarlie Plaisance-BonstaffSteven R. PostZhiqiang QinNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-6 (2021) |
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DOAJ |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Jungang Chen Lu Dai Lindsey Barrett Jennifer James Karlie Plaisance-Bonstaff Steven R. Post Zhiqiang Qin SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus |
description |
Chen et al. find that SARS-CoV-2 encoded proteins and some anti-COVID-19 drugs can induce lytic reactivation of Kaposi’s sarcoma-associated herpesvirus (KSHV), one of the major human oncogenic viruses. This study suggests that KSHV-positive patients exposed to COVID-19 or undergoing its treatment may have increased risks to develop virus-associated cancers, even after they have fully recovered from COVID-19. |
format |
article |
author |
Jungang Chen Lu Dai Lindsey Barrett Jennifer James Karlie Plaisance-Bonstaff Steven R. Post Zhiqiang Qin |
author_facet |
Jungang Chen Lu Dai Lindsey Barrett Jennifer James Karlie Plaisance-Bonstaff Steven R. Post Zhiqiang Qin |
author_sort |
Jungang Chen |
title |
SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus |
title_short |
SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus |
title_full |
SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus |
title_fullStr |
SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus |
title_full_unstemmed |
SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus |
title_sort |
sars-cov-2 proteins and anti-covid-19 drugs induce lytic reactivation of an oncogenic virus |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/c4ba9901e2664db29bea3935dc8d1547 |
work_keys_str_mv |
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1718379312037494784 |