Preexisting heart failure with reduced ejection fraction attenuates renal fibrosis after ischemia reperfusion via sympathetic activation

Abstract Although chronic heart failure is clinically associated with acute kidney injury (AKI), the precise mechanism that connects kidney and heart remains unknown. Here, we elucidate the effect of pre-existing heart failure with reduced ejection fraction (HFrEF) on kidney via sympathetic activity...

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Autores principales: Ryo Matsuura, Tetsushi Yamashita, Naoki Hayase, Yoshifumi Hamasaki, Eisei Noiri, Genri Numata, Eiki Takimoto, Masaomi Nangaku, Kent Doi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c4c2ada1e8b048e78937f72e4290ce63
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