Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis

Probiotics have tumour-suppressive effects in cancer cell lines and in animal models. In this study, the authors demonstrate that ferrichrome produced by Lactobacillus caseiATCC334 can suppress colon cancer growth inducing apoptosis via the JNK pathway.

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Detalles Bibliográficos
Autores principales: Hiroaki Konishi, Mikihiro Fujiya, Hiroki Tanaka, Nobuhiro Ueno, Kentaro Moriichi, Junpei Sasajima, Katsuya Ikuta, Hiroaki Akutsu, Hiroki Tanabe, Yutaka Kohgo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c4ceb1f2b8544f46a5921775d0f7f5a6
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Descripción
Sumario:Probiotics have tumour-suppressive effects in cancer cell lines and in animal models. In this study, the authors demonstrate that ferrichrome produced by Lactobacillus caseiATCC334 can suppress colon cancer growth inducing apoptosis via the JNK pathway.