Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis

Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis

Probiotics have tumour-suppressive effects in cancer cell lines and in animal models. In this study, the authors demonstrate that ferrichrome produced by Lactobacillus caseiATCC334 can suppress colon cancer growth inducing apoptosis via the JNK pathway.

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Autores principales: Hiroaki Konishi, Mikihiro Fujiya, Hiroki Tanaka, Nobuhiro Ueno, Kentaro Moriichi, Junpei Sasajima, Katsuya Ikuta, Hiroaki Akutsu, Hiroki Tanabe, Yutaka Kohgo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c4ceb1f2b8544f46a5921775d0f7f5a6
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spelling oai:doaj.org-article:c4ceb1f2b8544f46a5921775d0f7f5a62021-12-02T14:39:35ZProbiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis10.1038/ncomms123652041-1723https://doaj.org/article/c4ceb1f2b8544f46a5921775d0f7f5a62016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12365https://doaj.org/toc/2041-1723Probiotics have tumour-suppressive effects in cancer cell lines and in animal models. In this study, the authors demonstrate that ferrichrome produced by Lactobacillus caseiATCC334 can suppress colon cancer growth inducing apoptosis via the JNK pathway.Hiroaki KonishiMikihiro FujiyaHiroki TanakaNobuhiro UenoKentaro MoriichiJunpei SasajimaKatsuya IkutaHiroaki AkutsuHiroki TanabeYutaka KohgoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hiroaki Konishi
Mikihiro Fujiya
Hiroki Tanaka
Nobuhiro Ueno
Kentaro Moriichi
Junpei Sasajima
Katsuya Ikuta
Hiroaki Akutsu
Hiroki Tanabe
Yutaka Kohgo
Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
description Probiotics have tumour-suppressive effects in cancer cell lines and in animal models. In this study, the authors demonstrate that ferrichrome produced by Lactobacillus caseiATCC334 can suppress colon cancer growth inducing apoptosis via the JNK pathway.
format article
author Hiroaki Konishi
Mikihiro Fujiya
Hiroki Tanaka
Nobuhiro Ueno
Kentaro Moriichi
Junpei Sasajima
Katsuya Ikuta
Hiroaki Akutsu
Hiroki Tanabe
Yutaka Kohgo
author_facet Hiroaki Konishi
Mikihiro Fujiya
Hiroki Tanaka
Nobuhiro Ueno
Kentaro Moriichi
Junpei Sasajima
Katsuya Ikuta
Hiroaki Akutsu
Hiroki Tanabe
Yutaka Kohgo
author_sort Hiroaki Konishi
title Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
title_short Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
title_full Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
title_fullStr Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
title_full_unstemmed Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
title_sort probiotic-derived ferrichrome inhibits colon cancer progression via jnk-mediated apoptosis
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c4ceb1f2b8544f46a5921775d0f7f5a6
work_keys_str_mv AT hiroakikonishi probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT mikihirofujiya probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT hirokitanaka probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT nobuhiroueno probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT kentaromoriichi probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT junpeisasajima probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT katsuyaikuta probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT hiroakiakutsu probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT hirokitanabe probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
AT yutakakohgo probioticderivedferrichromeinhibitscoloncancerprogressionviajnkmediatedapoptosis
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