Sfrp3 modulates stromal–epithelial crosstalk during mammary gland development by regulating Wnt levels

The signalling pathways regulating how the mammary gland stroma interacts with the epithelia to then regulate gland development are unclear. Here, the authors identify Sfrp3 as regulating stroma communication via Wnts, on deletion, this increases ductal invasion and initiates an early pregnancy stat...

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Autores principales: Ilenia Bernascone, Tamara González, Maria D. Barea, Claudia Carabaña, Mariam Hachimi, Minerva Bosch-Fortea, Silvia Santamaria, Raquel Martin, Julia Tarnick, Jose A. Garcia-Sanz, Fernando Martín-Belmonte
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c4d0a69819984d5cb45e409bbfe44df3
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