A combination of transcriptional and microRNA regulation improves the stability of the relative concentrations of target genes.

It is well known that, under suitable conditions, microRNAs are able to fine tune the relative concentration of their targets to any desired value. We show that this function is particularly effective when one of the targets is a Transcription Factor (TF) which regulates the other targets. This comb...

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Autores principales: Andrea Riba, Carla Bosia, Mariama El Baroudi, Laura Ollino, Michele Caselle
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/c4d9535c59ab42b895610361c47a6295
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