Extreme inbreeding in a European ancestry sample from the contemporary UK population

Mating between first or second-degree relatives is prohibited in most countries, yet it occurs and is under-studied. Here, Yengo et al. use large runs of homozygosity from the UK Biobank resource to provide DNA-based quantification of extreme inbreeding and its consequence for health and other compl...

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Bibliographic Details
Main Authors: Loic Yengo, Naomi R. Wray, Peter M. Visscher
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/c4de637591d1426c8bf1b0307e7f96ad
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