Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity.
Protein aggregation into amyloid fibrils and protofibrillar aggregates is associated with a number of the most common neurodegenerative diseases. We have established, using a computational approach, that knowledge of the primary sequences of proteins is sufficient to predict their in vitro aggregati...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2007
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/c4e1adf9f10c4b98853de2fa4e79ca68 |
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