Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma

There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling.

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Autores principales: Xiao-Yan Ming, Li Fu, Li-Yi Zhang, Yan-Ru Qin, Ting-Ting Cao, Kwok Wah Chan, Stephanie Ma, Dan Xie, Xin-Yuan Guan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c4e41a7639424cc9a91de517acbe0487
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spelling oai:doaj.org-article:c4e41a7639424cc9a91de517acbe04872021-12-02T16:50:13ZIntegrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma10.1038/ncomms135682041-1723https://doaj.org/article/c4e41a7639424cc9a91de517acbe04872016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13568https://doaj.org/toc/2041-1723There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling.Xiao-Yan MingLi FuLi-Yi ZhangYan-Ru QinTing-Ting CaoKwok Wah ChanStephanie MaDan XieXin-Yuan GuanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiao-Yan Ming
Li Fu
Li-Yi Zhang
Yan-Ru Qin
Ting-Ting Cao
Kwok Wah Chan
Stephanie Ma
Dan Xie
Xin-Yuan Guan
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
description There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling.
format article
author Xiao-Yan Ming
Li Fu
Li-Yi Zhang
Yan-Ru Qin
Ting-Ting Cao
Kwok Wah Chan
Stephanie Ma
Dan Xie
Xin-Yuan Guan
author_facet Xiao-Yan Ming
Li Fu
Li-Yi Zhang
Yan-Ru Qin
Ting-Ting Cao
Kwok Wah Chan
Stephanie Ma
Dan Xie
Xin-Yuan Guan
author_sort Xiao-Yan Ming
title Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
title_short Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
title_full Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
title_fullStr Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
title_full_unstemmed Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
title_sort integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c4e41a7639424cc9a91de517acbe0487
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