Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling.
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Nature Portfolio
2016
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oai:doaj.org-article:c4e41a7639424cc9a91de517acbe04872021-12-02T16:50:13ZIntegrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma10.1038/ncomms135682041-1723https://doaj.org/article/c4e41a7639424cc9a91de517acbe04872016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13568https://doaj.org/toc/2041-1723There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling.Xiao-Yan MingLi FuLi-Yi ZhangYan-Ru QinTing-Ting CaoKwok Wah ChanStephanie MaDan XieXin-Yuan GuanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
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Science Q Xiao-Yan Ming Li Fu Li-Yi Zhang Yan-Ru Qin Ting-Ting Cao Kwok Wah Chan Stephanie Ma Dan Xie Xin-Yuan Guan Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma |
description |
There is still no consensus on tumour type-specific cancer stem cell markers. Here, the authors demonstrate that ITGA7 is a potential functional marker of oesophageal cancer stem cells involved in the resistance to chemotherapy and metastasis through activation of FAK-mediated signalling. |
format |
article |
author |
Xiao-Yan Ming Li Fu Li-Yi Zhang Yan-Ru Qin Ting-Ting Cao Kwok Wah Chan Stephanie Ma Dan Xie Xin-Yuan Guan |
author_facet |
Xiao-Yan Ming Li Fu Li-Yi Zhang Yan-Ru Qin Ting-Ting Cao Kwok Wah Chan Stephanie Ma Dan Xie Xin-Yuan Guan |
author_sort |
Xiao-Yan Ming |
title |
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma |
title_short |
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma |
title_full |
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma |
title_fullStr |
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma |
title_full_unstemmed |
Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma |
title_sort |
integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/c4e41a7639424cc9a91de517acbe0487 |
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