Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration

David McKellar et al. integrate single-cell and -nuclear transcriptomic analyses of mouse skeletal muscle in homeostatic conditions or following injury. The resulting transcriptomic model of myogenesis identified rare, transitional states and cell subtypes that are poorly represented in individual d...

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Autores principales: David W. McKellar, Lauren D. Walter, Leo T. Song, Madhav Mantri, Michael F. Z. Wang, Iwijn De Vlaminck, Benjamin D. Cosgrove
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c4f3d62d830e41acb90880a9b21a949c
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spelling oai:doaj.org-article:c4f3d62d830e41acb90880a9b21a949c2021-11-14T12:12:18ZLarge-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration10.1038/s42003-021-02810-x2399-3642https://doaj.org/article/c4f3d62d830e41acb90880a9b21a949c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02810-xhttps://doaj.org/toc/2399-3642David McKellar et al. integrate single-cell and -nuclear transcriptomic analyses of mouse skeletal muscle in homeostatic conditions or following injury. The resulting transcriptomic model of myogenesis identified rare, transitional states and cell subtypes that are poorly represented in individual datasets, providing a valuable resource for the field.David W. McKellarLauren D. WalterLeo T. SongMadhav MantriMichael F. Z. WangIwijn De VlaminckBenjamin D. CosgroveNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
David W. McKellar
Lauren D. Walter
Leo T. Song
Madhav Mantri
Michael F. Z. Wang
Iwijn De Vlaminck
Benjamin D. Cosgrove
Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
description David McKellar et al. integrate single-cell and -nuclear transcriptomic analyses of mouse skeletal muscle in homeostatic conditions or following injury. The resulting transcriptomic model of myogenesis identified rare, transitional states and cell subtypes that are poorly represented in individual datasets, providing a valuable resource for the field.
format article
author David W. McKellar
Lauren D. Walter
Leo T. Song
Madhav Mantri
Michael F. Z. Wang
Iwijn De Vlaminck
Benjamin D. Cosgrove
author_facet David W. McKellar
Lauren D. Walter
Leo T. Song
Madhav Mantri
Michael F. Z. Wang
Iwijn De Vlaminck
Benjamin D. Cosgrove
author_sort David W. McKellar
title Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
title_short Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
title_full Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
title_fullStr Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
title_full_unstemmed Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
title_sort large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c4f3d62d830e41acb90880a9b21a949c
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