Mechanosensitive channel YnaI has lipid-bound extended sensor paddles
Hu, Wang & Zheng describe the cryo-EM structure of a bacterial MscS-like channel, named YnaI, in closed state. They further describe its extended paddle domain that is attached to the N-terminus of MscS, lipid pockets between paddles, its ion-conducting pathway, and its heptameric assembly, fina...
Guardado en:
Autores principales: | , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c4f83f029ffe4e5a80ba716cb0c6ead4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:c4f83f029ffe4e5a80ba716cb0c6ead4 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:c4f83f029ffe4e5a80ba716cb0c6ead42021-12-02T16:49:37ZMechanosensitive channel YnaI has lipid-bound extended sensor paddles10.1038/s42003-021-02122-02399-3642https://doaj.org/article/c4f83f029ffe4e5a80ba716cb0c6ead42021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02122-0https://doaj.org/toc/2399-3642Hu, Wang & Zheng describe the cryo-EM structure of a bacterial MscS-like channel, named YnaI, in closed state. They further describe its extended paddle domain that is attached to the N-terminus of MscS, lipid pockets between paddles, its ion-conducting pathway, and its heptameric assembly, finally discussing its mechanosensing mechanism.Wenxin HuZhiming WangHongjin ZhengNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Biology (General) QH301-705.5 |
spellingShingle |
Biology (General) QH301-705.5 Wenxin Hu Zhiming Wang Hongjin Zheng Mechanosensitive channel YnaI has lipid-bound extended sensor paddles |
description |
Hu, Wang & Zheng describe the cryo-EM structure of a bacterial MscS-like channel, named YnaI, in closed state. They further describe its extended paddle domain that is attached to the N-terminus of MscS, lipid pockets between paddles, its ion-conducting pathway, and its heptameric assembly, finally discussing its mechanosensing mechanism. |
format |
article |
author |
Wenxin Hu Zhiming Wang Hongjin Zheng |
author_facet |
Wenxin Hu Zhiming Wang Hongjin Zheng |
author_sort |
Wenxin Hu |
title |
Mechanosensitive channel YnaI has lipid-bound extended sensor paddles |
title_short |
Mechanosensitive channel YnaI has lipid-bound extended sensor paddles |
title_full |
Mechanosensitive channel YnaI has lipid-bound extended sensor paddles |
title_fullStr |
Mechanosensitive channel YnaI has lipid-bound extended sensor paddles |
title_full_unstemmed |
Mechanosensitive channel YnaI has lipid-bound extended sensor paddles |
title_sort |
mechanosensitive channel ynai has lipid-bound extended sensor paddles |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/c4f83f029ffe4e5a80ba716cb0c6ead4 |
work_keys_str_mv |
AT wenxinhu mechanosensitivechannelynaihaslipidboundextendedsensorpaddles AT zhimingwang mechanosensitivechannelynaihaslipidboundextendedsensorpaddles AT hongjinzheng mechanosensitivechannelynaihaslipidboundextendedsensorpaddles |
_version_ |
1718383301894340608 |