CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes.
To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging transgenic mice (TG) overexpressing CCN2 driven by the Col2a1 promoter. Knee joints from 3-, 14-, 40-, and 60-day-old and 5-, 12-, 1...
Guardado en:
Autores principales: | Shinsuke Itoh, Takako Hattori, Nao Tomita, Eriko Aoyama, Yasutaka Yutani, Takashi Yamashiro, Masaharu Takigawa |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c50853a2a7cd43c2a0a53e1e6f138c6a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth.
por: Nao Tomita, et al.
Publicado: (2013) -
QoS Improvement Using In-Network Caching Based on Clustering and Popularity Heuristics in CCN
por: Sumit Kumar, et al.
Publicado: (2021) -
CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling
por: Joon-Il Jun, et al.
Publicado: (2020) -
WISP1/CCN4 inhibits adipocyte differentiation through repression of PPARγ activity
por: Nathalie Ferrand, et al.
Publicado: (2017) -
Modular network mechanism of CCN1-associated resistance to HSV-1-derived oncolytic immunovirotherapies for glioblastomas
por: Dileep D. Monie, et al.
Publicado: (2021)