Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy

Liam D Price,1 Stephanie Au,2 N Victor Chong1 1Oxford Eye Hospital, University of Oxford, Oxford, UK; 2University of Hong Kong, Hong Kong SAR, People’s Republic of China Purpose: To compare diabetic retinopathy (DR) severity grading between Optomap ultrawide field scanning laser ophthalmo...

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Autores principales: Price LD, Au S, Chong NV
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Publicado: Dove Medical Press 2015
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spelling oai:doaj.org-article:c50e126058c942c4af81058e07b9132f2021-12-02T10:54:28ZOptomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy1177-5483https://doaj.org/article/c50e126058c942c4af81058e07b9132f2015-03-01T00:00:00Zhttp://www.dovepress.com/optomap-ultrawide-field-imaging-identifies-additional-retinal-abnormal-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Liam D Price,1 Stephanie Au,2 N Victor Chong1 1Oxford Eye Hospital, University of Oxford, Oxford, UK; 2University of Hong Kong, Hong Kong SAR, People’s Republic of China Purpose: To compare diabetic retinopathy (DR) severity grading between Optomap ultrawide field scanning laser ophthalmoscope (UWFSLO) 200° images and an Early Treatment Diabetic Retinopathy Study (ETDRS) seven-standard field view.Methods: Optomap UWFSLO images (total: 266) were retrospectively selected for evidence of DR from a database of eye clinic attendees. The Optomap UWFSLO images were graded for DR severity by two masked assessors. An ETDRS seven-field mask was overlaid on the Optomap UWFSLO images, and the DR grade was assessed for the region inside the mask. Any interassessor discrepancies were adjudicated by a senior retinal specialist. Kappa agreement levels were used for statistical analysis.Results: Fifty images (19%) (P<0.001) were assigned a higher DR level in the Optomap UWFSLO view compared to the ETDRS seven-field view, which resulted in 40 images (15%) (P<0.001) receiving a higher DR severity grade. DR severity grades in the ETDRS seven-field view compared with the Optomap UWFSLO view were identical in 85% (226) of the images and within one severity level in 100% (266) of the images. Agreement between the two views was substantial: unweighted κ was 0.74±0.04 (95% confidence interval: 0.67–0.81) and weighted κ was 0.80±0.03 (95% confidence interval: 0.74–0.86).Conclusion: Compared to the ETDRS seven-field view, a significant minority of patients are diagnosed with more severe DR when using the Optomap UWFSLO view. The clinical significance of additional peripheral lesions requires evaluation in future prospective studies using large cohorts.Keywords: diagnostic imaging, diabetes, retinaPrice LDAu SChong NVDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 527-531 (2015)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Price LD
Au S
Chong NV
Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy
description Liam D Price,1 Stephanie Au,2 N Victor Chong1 1Oxford Eye Hospital, University of Oxford, Oxford, UK; 2University of Hong Kong, Hong Kong SAR, People’s Republic of China Purpose: To compare diabetic retinopathy (DR) severity grading between Optomap ultrawide field scanning laser ophthalmoscope (UWFSLO) 200° images and an Early Treatment Diabetic Retinopathy Study (ETDRS) seven-standard field view.Methods: Optomap UWFSLO images (total: 266) were retrospectively selected for evidence of DR from a database of eye clinic attendees. The Optomap UWFSLO images were graded for DR severity by two masked assessors. An ETDRS seven-field mask was overlaid on the Optomap UWFSLO images, and the DR grade was assessed for the region inside the mask. Any interassessor discrepancies were adjudicated by a senior retinal specialist. Kappa agreement levels were used for statistical analysis.Results: Fifty images (19%) (P<0.001) were assigned a higher DR level in the Optomap UWFSLO view compared to the ETDRS seven-field view, which resulted in 40 images (15%) (P<0.001) receiving a higher DR severity grade. DR severity grades in the ETDRS seven-field view compared with the Optomap UWFSLO view were identical in 85% (226) of the images and within one severity level in 100% (266) of the images. Agreement between the two views was substantial: unweighted κ was 0.74±0.04 (95% confidence interval: 0.67–0.81) and weighted κ was 0.80±0.03 (95% confidence interval: 0.74–0.86).Conclusion: Compared to the ETDRS seven-field view, a significant minority of patients are diagnosed with more severe DR when using the Optomap UWFSLO view. The clinical significance of additional peripheral lesions requires evaluation in future prospective studies using large cohorts.Keywords: diagnostic imaging, diabetes, retina
format article
author Price LD
Au S
Chong NV
author_facet Price LD
Au S
Chong NV
author_sort Price LD
title Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy
title_short Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy
title_full Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy
title_fullStr Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy
title_full_unstemmed Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy
title_sort optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/c50e126058c942c4af81058e07b9132f
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AT aus optomapultrawidefieldimagingidentifiesadditionalretinalabnormalitiesinpatientswithnbspdiabeticretinopathy
AT chongnv optomapultrawidefieldimagingidentifiesadditionalretinalabnormalitiesinpatientswithnbspdiabeticretinopathy
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