Distinct pre-initiation steps in human mitochondrial translation

Translation within mitochondria relies upon specialized mitoribosomes and initiation factors. Here the authors use Cryo-EM and single molecule approaches to describe the early steps leading to translation initiation in human mitochondria, and the roles of mitochondria-specific ribosomal proteins and...

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Autores principales:	Anas Khawaja, Yuzuru Itoh, Cristina Remes, Henrik Spåhr, Olessya Yukhnovets, Henning Höfig, Alexey Amunts, Joanna Rorbach
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c511e0e642764f37845e6699bdca4970
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spelling	oai:doaj.org-article:c511e0e642764f37845e6699bdca49702021-12-02T17:52:20ZDistinct pre-initiation steps in human mitochondrial translation10.1038/s41467-020-16503-22041-1723https://doaj.org/article/c511e0e642764f37845e6699bdca49702020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16503-2https://doaj.org/toc/2041-1723Translation within mitochondria relies upon specialized mitoribosomes and initiation factors. Here the authors use Cryo-EM and single molecule approaches to describe the early steps leading to translation initiation in human mitochondria, and the roles of mitochondria-specific ribosomal proteins and initiation factors mtIF2 and mtIF3.Anas KhawajaYuzuru ItohCristina RemesHenrik SpåhrOlessya YukhnovetsHenning HöfigAlexey AmuntsJoanna RorbachNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anas Khawaja Yuzuru Itoh Cristina Remes Henrik Spåhr Olessya Yukhnovets Henning Höfig Alexey Amunts Joanna Rorbach Distinct pre-initiation steps in human mitochondrial translation
description	Translation within mitochondria relies upon specialized mitoribosomes and initiation factors. Here the authors use Cryo-EM and single molecule approaches to describe the early steps leading to translation initiation in human mitochondria, and the roles of mitochondria-specific ribosomal proteins and initiation factors mtIF2 and mtIF3.
format	article
author	Anas Khawaja Yuzuru Itoh Cristina Remes Henrik Spåhr Olessya Yukhnovets Henning Höfig Alexey Amunts Joanna Rorbach
author_facet	Anas Khawaja Yuzuru Itoh Cristina Remes Henrik Spåhr Olessya Yukhnovets Henning Höfig Alexey Amunts Joanna Rorbach
author_sort	Anas Khawaja
title	Distinct pre-initiation steps in human mitochondrial translation
title_short	Distinct pre-initiation steps in human mitochondrial translation
title_full	Distinct pre-initiation steps in human mitochondrial translation
title_fullStr	Distinct pre-initiation steps in human mitochondrial translation
title_full_unstemmed	Distinct pre-initiation steps in human mitochondrial translation
title_sort	distinct pre-initiation steps in human mitochondrial translation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c511e0e642764f37845e6699bdca4970
work_keys_str_mv	AT anaskhawaja distinctpreinitiationstepsinhumanmitochondrialtranslation AT yuzuruitoh distinctpreinitiationstepsinhumanmitochondrialtranslation AT cristinaremes distinctpreinitiationstepsinhumanmitochondrialtranslation AT henrikspahr distinctpreinitiationstepsinhumanmitochondrialtranslation AT olessyayukhnovets distinctpreinitiationstepsinhumanmitochondrialtranslation AT henninghofig distinctpreinitiationstepsinhumanmitochondrialtranslation AT alexeyamunts distinctpreinitiationstepsinhumanmitochondrialtranslation AT joannarorbach distinctpreinitiationstepsinhumanmitochondrialtranslation
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Distinct pre-initiation steps in human mitochondrial translation

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