Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions

Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases encountered in primary care and gastroenterology clinics. Most cases of GERD can be diagnosed based on clinical presentation and risk factors; however, some patients present with atypical symptoms, which can m...

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Autores principales: Rupinder Mann, Mahesh Gajendran, Abhilash Perisetti, Hemant Goyal, Shreyas Saligram, Chandraprakash Umapathy
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/c519e349e110432d98b4b8ae051eaa57
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spelling oai:doaj.org-article:c519e349e110432d98b4b8ae051eaa572021-12-01T13:08:08ZAdvanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions2296-858X10.3389/fmed.2021.728696https://doaj.org/article/c519e349e110432d98b4b8ae051eaa572021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.728696/fullhttps://doaj.org/toc/2296-858XGastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases encountered in primary care and gastroenterology clinics. Most cases of GERD can be diagnosed based on clinical presentation and risk factors; however, some patients present with atypical symptoms, which can make diagnosis difficult. An esophagogastroduodenoscopy can be used to assist in diagnosis of GERD, though only half of these patients have visible endoscopic findings on standard white light endoscopy. This led to the development of new advanced endoscopic techniques that enhanced the diagnosis of GERD and related complications like squamous cell dysplasia, Barrett's esophagus, and early esophageal adenocarcinoma. This is conducted by improved detection of subtle irregularities in the mucosa and vascular structures through optical biopsies in real-time. Management of GERD includes lifestyle modifications, pharmacological therapy, endoscopic and surgical intervention. Minimally invasive endoscopic intervention can be an option in selected patients with small hiatal hernia and without complications of GERD. These endoscopic interventions include endoscopic fundoplication, endoscopic mucosal resection techniques, ablative techniques, creating mechanical barriers, and suturing and stapling devices. As these new advanced endoscopic techniques are emerging, data surrounding the indications, advantages and disadvantages of these techniques need a thorough understanding.Rupinder MannMahesh GajendranAbhilash PerisettiAbhilash PerisettiHemant GoyalShreyas SaligramChandraprakash UmapathyFrontiers Media S.A.articlegastroesophageal reflux disease (GERD)endoscopic reflux therapynarrow band imaging (NBI)endoscopyBarrett's esophagus (BE)Medicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution DOAJ
collection DOAJ
language EN
topic gastroesophageal reflux disease (GERD)
endoscopic reflux therapy
narrow band imaging (NBI)
endoscopy
Barrett's esophagus (BE)
Medicine (General)
R5-920
spellingShingle gastroesophageal reflux disease (GERD)
endoscopic reflux therapy
narrow band imaging (NBI)
endoscopy
Barrett's esophagus (BE)
Medicine (General)
R5-920
Rupinder Mann
Mahesh Gajendran
Abhilash Perisetti
Abhilash Perisetti
Hemant Goyal
Shreyas Saligram
Chandraprakash Umapathy
Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions
description Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases encountered in primary care and gastroenterology clinics. Most cases of GERD can be diagnosed based on clinical presentation and risk factors; however, some patients present with atypical symptoms, which can make diagnosis difficult. An esophagogastroduodenoscopy can be used to assist in diagnosis of GERD, though only half of these patients have visible endoscopic findings on standard white light endoscopy. This led to the development of new advanced endoscopic techniques that enhanced the diagnosis of GERD and related complications like squamous cell dysplasia, Barrett's esophagus, and early esophageal adenocarcinoma. This is conducted by improved detection of subtle irregularities in the mucosa and vascular structures through optical biopsies in real-time. Management of GERD includes lifestyle modifications, pharmacological therapy, endoscopic and surgical intervention. Minimally invasive endoscopic intervention can be an option in selected patients with small hiatal hernia and without complications of GERD. These endoscopic interventions include endoscopic fundoplication, endoscopic mucosal resection techniques, ablative techniques, creating mechanical barriers, and suturing and stapling devices. As these new advanced endoscopic techniques are emerging, data surrounding the indications, advantages and disadvantages of these techniques need a thorough understanding.
format article
author Rupinder Mann
Mahesh Gajendran
Abhilash Perisetti
Abhilash Perisetti
Hemant Goyal
Shreyas Saligram
Chandraprakash Umapathy
author_facet Rupinder Mann
Mahesh Gajendran
Abhilash Perisetti
Abhilash Perisetti
Hemant Goyal
Shreyas Saligram
Chandraprakash Umapathy
author_sort Rupinder Mann
title Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions
title_short Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions
title_full Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions
title_fullStr Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions
title_full_unstemmed Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions
title_sort advanced endoscopic imaging and interventions in gerd: an update and future directions
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/c519e349e110432d98b4b8ae051eaa57
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AT abhilashperisetti advancedendoscopicimagingandinterventionsingerdanupdateandfuturedirections
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