Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty

Abstract The purpose of this present study was to investigate predictive clinical factors associated with cystoid macular edema (CME) post Descemet’s stripping automated endothelial keratoplasty (DSAEK) in a large case series. Of 393 consecutive patients who underwent DSAEK at Baptist Eye Institute,...

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Autores principales:	Koji Kitazawa, Kanae Kayukawa, Koichi Wakimasu, Isao Yokota, Tsutomu Inatomi, Osamu Hieda, Kazuhiko Mori, Chie Sotozono, Shigeru Kinoshita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c51f663058b643b0b29a54cfa209b3f7
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spelling	oai:doaj.org-article:c51f663058b643b0b29a54cfa209b3f72021-12-02T12:32:41ZPredictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty10.1038/s41598-017-07079-x2045-2322https://doaj.org/article/c51f663058b643b0b29a54cfa209b3f72017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07079-xhttps://doaj.org/toc/2045-2322Abstract The purpose of this present study was to investigate predictive clinical factors associated with cystoid macular edema (CME) post Descemet’s stripping automated endothelial keratoplasty (DSAEK) in a large case series. Of 393 consecutive patients who underwent DSAEK at Baptist Eye Institute, Kyoto, Japan between July 2011 and November 2016, 241 patients without CME at the pre- or early-postoperative periods were enrolled. The occurrence of anatomic CME was prospectively examined via optical coherence tomography (OCT). Possible predictive clinical factors for CME were analyzed by multivariate logistic regression analysis. At 1-month post DSAEK, CME occurred in 27 (11.2%) of the 241 patients. Multivariate analysis revealed that primary angle closure glaucoma (PACG) was significantly associated with postoperative CME (odds ratio = 6.4, P = 0.04). The findings of this study revealed that DSAEK in patients with PACG showed a high incidence of CME, thus indicating that they should undergo a careful postoperative observation of the macula via OCT.Koji KitazawaKanae KayukawaKoichi WakimasuIsao YokotaTsutomu InatomiOsamu HiedaKazuhiko MoriChie SotozonoShigeru KinoshitaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Koji Kitazawa Kanae Kayukawa Koichi Wakimasu Isao Yokota Tsutomu Inatomi Osamu Hieda Kazuhiko Mori Chie Sotozono Shigeru Kinoshita Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty
description	Abstract The purpose of this present study was to investigate predictive clinical factors associated with cystoid macular edema (CME) post Descemet’s stripping automated endothelial keratoplasty (DSAEK) in a large case series. Of 393 consecutive patients who underwent DSAEK at Baptist Eye Institute, Kyoto, Japan between July 2011 and November 2016, 241 patients without CME at the pre- or early-postoperative periods were enrolled. The occurrence of anatomic CME was prospectively examined via optical coherence tomography (OCT). Possible predictive clinical factors for CME were analyzed by multivariate logistic regression analysis. At 1-month post DSAEK, CME occurred in 27 (11.2%) of the 241 patients. Multivariate analysis revealed that primary angle closure glaucoma (PACG) was significantly associated with postoperative CME (odds ratio = 6.4, P = 0.04). The findings of this study revealed that DSAEK in patients with PACG showed a high incidence of CME, thus indicating that they should undergo a careful postoperative observation of the macula via OCT.
format	article
author	Koji Kitazawa Kanae Kayukawa Koichi Wakimasu Isao Yokota Tsutomu Inatomi Osamu Hieda Kazuhiko Mori Chie Sotozono Shigeru Kinoshita
author_facet	Koji Kitazawa Kanae Kayukawa Koichi Wakimasu Isao Yokota Tsutomu Inatomi Osamu Hieda Kazuhiko Mori Chie Sotozono Shigeru Kinoshita
author_sort	Koji Kitazawa
title	Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty
title_short	Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty
title_full	Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty
title_fullStr	Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty
title_full_unstemmed	Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty
title_sort	predictive clinical factors of cystoid macular edema in patients with descemet’s stripping automated endothelial keratoplasty
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/c51f663058b643b0b29a54cfa209b3f7
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Predictive clinical factors of cystoid macular edema in patients with Descemet’s stripping automated endothelial keratoplasty

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