Expression Analysis and Mutational Status of Histone Methyltransferase <i>KMT2D</i> at Different Upper Tract Urothelial Carcinoma Locations

Expression Analysis and Mutational Status of Histone Methyltransferase <i>KMT2D</i> at Different Upper Tract Urothelial Carcinoma Locations

The gene coding for histone methyltransferase KMT2D is found among the top mutated genes in upper tract urothelial carcinoma (UTUC); however, there is a lack of data regarding its association with clinicopathologic features as well as survival outcomes. Therefore, we aimed to investigate <i>KM...

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Autores principales: Ekaterina Laukhtina, Ursula Lemberger, Andreas Bruchbacher, Dafina Ilijazi, Stephan Korn, Florian Berndl, David D’Andrea, Martin Susani, Dmitry Enikeev, Eva Compérat, Shahrokh F. Shariat, Melanie R. Hassler
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
UTUC
urothelial cancer
KMT2 family
KMT2D
histone methylation
Medicine
R
Acceso en línea:https://doaj.org/article/c526ef76eb804e4084c0ace6b81a2109
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