Split selectable markers

Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.

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Detalles Bibliográficos
Autores principales: Nathaniel Jillette, Menghan Du, Jacqueline Jufen Zhu, Peter Cardoz, Albert Wu Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c526fa456318455daf9b51a1e8c0784b
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Descripción
Sumario:Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.