Epigenetic changes in Basal Cell Carcinoma affect SHH and WNT signaling components.

Epigenetic changes in Basal Cell Carcinoma affect SHH and WNT signaling components.

<h4>Background</h4>The genetic background of Basal Cell Carcinoma (BCC) has been studied extensively, while its epigenetic makeup has received comparatively little attention. Epigenetic alterations such as promoter hypermethylation silence tumor suppressor genes (TSG) in several malignan...

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Autores principales: Tjinta Brinkhuizen, Karin van den Hurk, Véronique J L Winnepenninckx, Joep P de Hoon, Ariënne M van Marion, Jürgen Veeck, Manon van Engeland, Maurice A M van Steensel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/c538522c95144ee4a3d887164b480cdd
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