FMRP regulates STAT3 mRNA localization to cellular protrusions and local translation to promote hepatocellular carcinoma metastasis

FMRP regulates STAT3 mRNA localization to cellular protrusions and local translation to promote hepatocellular carcinoma metastasis

Shen et al. propose a mechanism for the metastasis of hepatocellular carcinoma (HCC) cells through the localization and translation modulation of the STAT3 oncogene by fragile X mental retardation protein (FMRP). To this end, the authors also find that FMRP knockdown efficiently suppresses HCC metas...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhifa Shen, Bowen Liu, Biting Wu, Hongyin Zhou, Xiangyun Wang, Jinling Cao, Min Jiang, Yingying Zhou, Feixia Guo, Chang Xue, Zai-Sheng Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/c5469822c028494c8fabd249667c6c12
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares