Takayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?

Coexistence of spondyloarthritis (SpA) and Takayasu’s arteritis is not a common finding, but such cases have been discussed, particularly in the context of choice of therapy. Inhibition of inflammation by tumor necrosis factor inhibitors (TNFi) is a key aspect of the treatment of SpA and also positi...

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Autores principales: Amel Rezgui, Maissa Thabet, Sahar Makki, Jihed Anoun, Imen Ben Hassine, Monia Karmeni, Fatma Ben Fredj, Anis Mzabi, Chedia Laouani
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Lenguaje:EN
Publicado: Termedia Publishing House 2021
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Acceso en línea:https://doaj.org/article/c5489f2a2a4a4b02865511d6628e14ab
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spelling oai:doaj.org-article:c5489f2a2a4a4b02865511d6628e14ab2021-12-02T18:55:18ZTakayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?0034-62332084-983410.5114/reum.2021.103394https://doaj.org/article/c5489f2a2a4a4b02865511d6628e14ab2021-02-01T00:00:00Zhttps://www.termedia.pl/Takayasu-s-arteritis-occurring-under-TNF-blockers-in-a-patient-with-spondyloarthritis-is-it-an-association-or-a-paradoxical-effect-,18,43206,1,1.htmlhttps://doaj.org/toc/0034-6233https://doaj.org/toc/2084-9834Coexistence of spondyloarthritis (SpA) and Takayasu’s arteritis is not a common finding, but such cases have been discussed, particularly in the context of choice of therapy. Inhibition of inflammation by tumor necrosis factor inhibitors (TNFi) is a key aspect of the treatment of SpA and also positive effects of such treatment in concomitant large vessel vasculitis have been reported. However, TNFi is also associated with the possibility of initiating vasculitis. The present article based on a case study and the available literature is an attempt to discuss coexistence of these two diseases and the impact of treatment with biological drugs from the anti-TNF group in the course of SpA with Takayasu’s arteritis.Amel RezguiMaissa ThabetSahar MakkiJihed AnounImen Ben HassineMonia KarmeniFatma Ben FredjAnis MzabiChedia LaouaniTermedia Publishing Housearticleankylosing spondylitis takayasu’s arteritis tumor necrosis factor.MedicineRENRheumatology, Vol 59, Iss 2, Pp 111-114 (2021)
institution DOAJ
collection DOAJ
language EN
topic ankylosing spondylitis
takayasu’s arteritis
tumor necrosis factor.
Medicine
R
spellingShingle ankylosing spondylitis
takayasu’s arteritis
tumor necrosis factor.
Medicine
R
Amel Rezgui
Maissa Thabet
Sahar Makki
Jihed Anoun
Imen Ben Hassine
Monia Karmeni
Fatma Ben Fredj
Anis Mzabi
Chedia Laouani
Takayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?
description Coexistence of spondyloarthritis (SpA) and Takayasu’s arteritis is not a common finding, but such cases have been discussed, particularly in the context of choice of therapy. Inhibition of inflammation by tumor necrosis factor inhibitors (TNFi) is a key aspect of the treatment of SpA and also positive effects of such treatment in concomitant large vessel vasculitis have been reported. However, TNFi is also associated with the possibility of initiating vasculitis. The present article based on a case study and the available literature is an attempt to discuss coexistence of these two diseases and the impact of treatment with biological drugs from the anti-TNF group in the course of SpA with Takayasu’s arteritis.
format article
author Amel Rezgui
Maissa Thabet
Sahar Makki
Jihed Anoun
Imen Ben Hassine
Monia Karmeni
Fatma Ben Fredj
Anis Mzabi
Chedia Laouani
author_facet Amel Rezgui
Maissa Thabet
Sahar Makki
Jihed Anoun
Imen Ben Hassine
Monia Karmeni
Fatma Ben Fredj
Anis Mzabi
Chedia Laouani
author_sort Amel Rezgui
title Takayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?
title_short Takayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?
title_full Takayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?
title_fullStr Takayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?
title_full_unstemmed Takayasu’s arteritis occurring under TNF blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?
title_sort takayasu’s arteritis occurring under tnf blockers in a patient with spondyloarthritis: is it an association or a paradoxical effect?
publisher Termedia Publishing House
publishDate 2021
url https://doaj.org/article/c5489f2a2a4a4b02865511d6628e14ab
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