Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika

Here, Andrade et al. assess the memory B cell (MBC) and antibody response to Zika virus (ZIKV) in individuals with and without prior dengue virus (DENV) infection and find that ZIKV infection elicits a robust and specific MBC response that is only modestly affected by the number of prior DENV infect...

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Autores principales: Paulina Andrade, Ciara Gimblet-Ochieng, Faraz Modirian, Matthew Collins, Maritza Cárdenas, Leah C. Katzelnick, Magelda Montoya, Daniela Michlmayr, Guillermina Kuan, Angel Balmaseda, Josefina Coloma, Aravinda M. de Silva, Eva Harris
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c554c8c491bc4839a274cc4a0886664d
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spelling oai:doaj.org-article:c554c8c491bc4839a274cc4a0886664d2021-12-02T14:38:36ZImpact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika10.1038/s41467-019-08845-32041-1723https://doaj.org/article/c554c8c491bc4839a274cc4a0886664d2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08845-3https://doaj.org/toc/2041-1723Here, Andrade et al. assess the memory B cell (MBC) and antibody response to Zika virus (ZIKV) in individuals with and without prior dengue virus (DENV) infection and find that ZIKV infection elicits a robust and specific MBC response that is only modestly affected by the number of prior DENV infections.Paulina AndradeCiara Gimblet-OchiengFaraz ModirianMatthew CollinsMaritza CárdenasLeah C. KatzelnickMagelda MontoyaDaniela MichlmayrGuillermina KuanAngel BalmasedaJosefina ColomaAravinda M. de SilvaEva HarrisNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Paulina Andrade
Ciara Gimblet-Ochieng
Faraz Modirian
Matthew Collins
Maritza Cárdenas
Leah C. Katzelnick
Magelda Montoya
Daniela Michlmayr
Guillermina Kuan
Angel Balmaseda
Josefina Coloma
Aravinda M. de Silva
Eva Harris
Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika
description Here, Andrade et al. assess the memory B cell (MBC) and antibody response to Zika virus (ZIKV) in individuals with and without prior dengue virus (DENV) infection and find that ZIKV infection elicits a robust and specific MBC response that is only modestly affected by the number of prior DENV infections.
format article
author Paulina Andrade
Ciara Gimblet-Ochieng
Faraz Modirian
Matthew Collins
Maritza Cárdenas
Leah C. Katzelnick
Magelda Montoya
Daniela Michlmayr
Guillermina Kuan
Angel Balmaseda
Josefina Coloma
Aravinda M. de Silva
Eva Harris
author_facet Paulina Andrade
Ciara Gimblet-Ochieng
Faraz Modirian
Matthew Collins
Maritza Cárdenas
Leah C. Katzelnick
Magelda Montoya
Daniela Michlmayr
Guillermina Kuan
Angel Balmaseda
Josefina Coloma
Aravinda M. de Silva
Eva Harris
author_sort Paulina Andrade
title Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika
title_short Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika
title_full Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika
title_fullStr Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika
title_full_unstemmed Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika
title_sort impact of pre-existing dengue immunity on human antibody and memory b cell responses to zika
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/c554c8c491bc4839a274cc4a0886664d
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