Transient Suppression of <named-content content-type="genus-species">Shigella flexneri</named-content> Type 3 Secretion by a Protective O-Antigen-Specific Monoclonal IgA

Transient Suppression of <named-content content-type="genus-species">Shigella flexneri</named-content> Type 3 Secretion by a Protective O-Antigen-Specific Monoclonal IgA

ABSTRACT Mucosal immunity to the enteric pathogen Shigella flexneri is mediated by secretory IgA (S-IgA) antibodies directed against the O-antigen (O-Ag) side chain of lipopolysaccharide. While secretory antibodies against the O-Ag are known to prevent bacterial invasion of the intestinal epithelium...

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Autores principales: Stephen J. Forbes, Tia Bumpus, Elizabeth A. McCarthy, Blaise Corthésy, Nicholas J. Mantis
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/c55926b829ee43c39ffdcd3a7ede6d6f
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