Meta-Analysis of Sleep Deprivation Effects on Patients With Depression

Objective: Depression is a common disorder with a high recurrence rate. Since the effect of sleep deprivation on depression in existing studies were inconsistent, the present study aimed to reassess the effects of SD on patients by performing a meta-analysis of updated research.Methods: PubMed, Emba...

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Autores principales: Baiqi Hu, Chunyan Liu, Tingting Mou, Fangyi Luo, Tingting Lv, Chao Qian, Jian Zhang, Mengfei Ye, Zheng Liu
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/c559c5444b8d43d0a670d8cbb009f9a2
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spelling oai:doaj.org-article:c559c5444b8d43d0a670d8cbb009f9a22021-12-01T15:37:11ZMeta-Analysis of Sleep Deprivation Effects on Patients With Depression1664-064010.3389/fpsyt.2021.783091https://doaj.org/article/c559c5444b8d43d0a670d8cbb009f9a22021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fpsyt.2021.783091/fullhttps://doaj.org/toc/1664-0640Objective: Depression is a common disorder with a high recurrence rate. Since the effect of sleep deprivation on depression in existing studies were inconsistent, the present study aimed to reassess the effects of SD on patients by performing a meta-analysis of updated research.Methods: PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 20th, 2021. Data on participant characteristics, SD characteristics, adjunctive method and tests for depression were extracted. A comprehensive analysis was conducted to assess the effect of SD on depression and subgroup analysis was used to determine the sources of heterogeneity.Results: In total, 8 articles were included. An SD time of <7 days slightly worsened depression levels [0.24 (−0.21, 0.69); I2 = 0%; P = 0.43], a time of 7–14 days had antidepressant effects [−1.52 (−2.07, −0.97); I2 = 19.6%; P = 0.288], and a time of more than 14 days also worsened depression [0.76 (0.12, 1.40); I2 = 43.7%; P = 0.169].Conclusion: SD may serve as an effective antidepressant measure in humans when the time was 7–14 days, while a time of <7 days and more than 14 days worsened depression.Baiqi HuBaiqi HuBaiqi HuChunyan LiuTingting MouFangyi LuoTingting LvChao QianJian ZhangMengfei YeZheng LiuFrontiers Media S.A.articlesleep deprivation (SD)depressionmeta-analysispatientsreviewPsychiatryRC435-571ENFrontiers in Psychiatry, Vol 12 (2021)
institution DOAJ
collection DOAJ
language EN
topic sleep deprivation (SD)
depression
meta-analysis
patients
review
Psychiatry
RC435-571
spellingShingle sleep deprivation (SD)
depression
meta-analysis
patients
review
Psychiatry
RC435-571
Baiqi Hu
Baiqi Hu
Baiqi Hu
Chunyan Liu
Tingting Mou
Fangyi Luo
Tingting Lv
Chao Qian
Jian Zhang
Mengfei Ye
Zheng Liu
Meta-Analysis of Sleep Deprivation Effects on Patients With Depression
description Objective: Depression is a common disorder with a high recurrence rate. Since the effect of sleep deprivation on depression in existing studies were inconsistent, the present study aimed to reassess the effects of SD on patients by performing a meta-analysis of updated research.Methods: PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 20th, 2021. Data on participant characteristics, SD characteristics, adjunctive method and tests for depression were extracted. A comprehensive analysis was conducted to assess the effect of SD on depression and subgroup analysis was used to determine the sources of heterogeneity.Results: In total, 8 articles were included. An SD time of <7 days slightly worsened depression levels [0.24 (−0.21, 0.69); I2 = 0%; P = 0.43], a time of 7–14 days had antidepressant effects [−1.52 (−2.07, −0.97); I2 = 19.6%; P = 0.288], and a time of more than 14 days also worsened depression [0.76 (0.12, 1.40); I2 = 43.7%; P = 0.169].Conclusion: SD may serve as an effective antidepressant measure in humans when the time was 7–14 days, while a time of <7 days and more than 14 days worsened depression.
format article
author Baiqi Hu
Baiqi Hu
Baiqi Hu
Chunyan Liu
Tingting Mou
Fangyi Luo
Tingting Lv
Chao Qian
Jian Zhang
Mengfei Ye
Zheng Liu
author_facet Baiqi Hu
Baiqi Hu
Baiqi Hu
Chunyan Liu
Tingting Mou
Fangyi Luo
Tingting Lv
Chao Qian
Jian Zhang
Mengfei Ye
Zheng Liu
author_sort Baiqi Hu
title Meta-Analysis of Sleep Deprivation Effects on Patients With Depression
title_short Meta-Analysis of Sleep Deprivation Effects on Patients With Depression
title_full Meta-Analysis of Sleep Deprivation Effects on Patients With Depression
title_fullStr Meta-Analysis of Sleep Deprivation Effects on Patients With Depression
title_full_unstemmed Meta-Analysis of Sleep Deprivation Effects on Patients With Depression
title_sort meta-analysis of sleep deprivation effects on patients with depression
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/c559c5444b8d43d0a670d8cbb009f9a2
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