Meta-Analysis of Sleep Deprivation Effects on Patients With Depression
Objective: Depression is a common disorder with a high recurrence rate. Since the effect of sleep deprivation on depression in existing studies were inconsistent, the present study aimed to reassess the effects of SD on patients by performing a meta-analysis of updated research.Methods: PubMed, Emba...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:c559c5444b8d43d0a670d8cbb009f9a22021-12-01T15:37:11ZMeta-Analysis of Sleep Deprivation Effects on Patients With Depression1664-064010.3389/fpsyt.2021.783091https://doaj.org/article/c559c5444b8d43d0a670d8cbb009f9a22021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fpsyt.2021.783091/fullhttps://doaj.org/toc/1664-0640Objective: Depression is a common disorder with a high recurrence rate. Since the effect of sleep deprivation on depression in existing studies were inconsistent, the present study aimed to reassess the effects of SD on patients by performing a meta-analysis of updated research.Methods: PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 20th, 2021. Data on participant characteristics, SD characteristics, adjunctive method and tests for depression were extracted. A comprehensive analysis was conducted to assess the effect of SD on depression and subgroup analysis was used to determine the sources of heterogeneity.Results: In total, 8 articles were included. An SD time of <7 days slightly worsened depression levels [0.24 (−0.21, 0.69); I2 = 0%; P = 0.43], a time of 7–14 days had antidepressant effects [−1.52 (−2.07, −0.97); I2 = 19.6%; P = 0.288], and a time of more than 14 days also worsened depression [0.76 (0.12, 1.40); I2 = 43.7%; P = 0.169].Conclusion: SD may serve as an effective antidepressant measure in humans when the time was 7–14 days, while a time of <7 days and more than 14 days worsened depression.Baiqi HuBaiqi HuBaiqi HuChunyan LiuTingting MouFangyi LuoTingting LvChao QianJian ZhangMengfei YeZheng LiuFrontiers Media S.A.articlesleep deprivation (SD)depressionmeta-analysispatientsreviewPsychiatryRC435-571ENFrontiers in Psychiatry, Vol 12 (2021) |
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sleep deprivation (SD) depression meta-analysis patients review Psychiatry RC435-571 |
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sleep deprivation (SD) depression meta-analysis patients review Psychiatry RC435-571 Baiqi Hu Baiqi Hu Baiqi Hu Chunyan Liu Tingting Mou Fangyi Luo Tingting Lv Chao Qian Jian Zhang Mengfei Ye Zheng Liu Meta-Analysis of Sleep Deprivation Effects on Patients With Depression |
description |
Objective: Depression is a common disorder with a high recurrence rate. Since the effect of sleep deprivation on depression in existing studies were inconsistent, the present study aimed to reassess the effects of SD on patients by performing a meta-analysis of updated research.Methods: PubMed, Embase, the Cochrane Library, and Web of Science were searched for articles before January 20th, 2021. Data on participant characteristics, SD characteristics, adjunctive method and tests for depression were extracted. A comprehensive analysis was conducted to assess the effect of SD on depression and subgroup analysis was used to determine the sources of heterogeneity.Results: In total, 8 articles were included. An SD time of <7 days slightly worsened depression levels [0.24 (−0.21, 0.69); I2 = 0%; P = 0.43], a time of 7–14 days had antidepressant effects [−1.52 (−2.07, −0.97); I2 = 19.6%; P = 0.288], and a time of more than 14 days also worsened depression [0.76 (0.12, 1.40); I2 = 43.7%; P = 0.169].Conclusion: SD may serve as an effective antidepressant measure in humans when the time was 7–14 days, while a time of <7 days and more than 14 days worsened depression. |
format |
article |
author |
Baiqi Hu Baiqi Hu Baiqi Hu Chunyan Liu Tingting Mou Fangyi Luo Tingting Lv Chao Qian Jian Zhang Mengfei Ye Zheng Liu |
author_facet |
Baiqi Hu Baiqi Hu Baiqi Hu Chunyan Liu Tingting Mou Fangyi Luo Tingting Lv Chao Qian Jian Zhang Mengfei Ye Zheng Liu |
author_sort |
Baiqi Hu |
title |
Meta-Analysis of Sleep Deprivation Effects on Patients With Depression |
title_short |
Meta-Analysis of Sleep Deprivation Effects on Patients With Depression |
title_full |
Meta-Analysis of Sleep Deprivation Effects on Patients With Depression |
title_fullStr |
Meta-Analysis of Sleep Deprivation Effects on Patients With Depression |
title_full_unstemmed |
Meta-Analysis of Sleep Deprivation Effects on Patients With Depression |
title_sort |
meta-analysis of sleep deprivation effects on patients with depression |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/c559c5444b8d43d0a670d8cbb009f9a2 |
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