Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation

Polymorphisms in the avian influenza A virus (IAV) polymerase restrict its host range during transmission from birds to mammals. Here, the authors investigate differences in the host chromatin regulator ANP32A regarding IAV polymerase adaptation, and profile ANP32A splicing to predict avian species...

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Autores principales:	Patricia Domingues, Davide Eletto, Carsten Magnus, Hannah L. Turkington, Stefan Schmutz, Osvaldo Zagordi, Matthias Lenk, Martin Beer, Silke Stertz, Benjamin G. Hale
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c571427377a442969ca7292bcf2a560b
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spelling	oai:doaj.org-article:c571427377a442969ca7292bcf2a560b2021-12-02T15:35:59ZProfiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation10.1038/s41467-019-11388-22041-1723https://doaj.org/article/c571427377a442969ca7292bcf2a560b2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11388-2https://doaj.org/toc/2041-1723Polymorphisms in the avian influenza A virus (IAV) polymerase restrict its host range during transmission from birds to mammals. Here, the authors investigate differences in the host chromatin regulator ANP32A regarding IAV polymerase adaptation, and profile ANP32A splicing to predict avian species associated with pre-adaptive human-signatures in the virus.Patricia DominguesDavide ElettoCarsten MagnusHannah L. TurkingtonStefan SchmutzOsvaldo ZagordiMatthias LenkMartin BeerSilke StertzBenjamin G. HaleNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Patricia Domingues Davide Eletto Carsten Magnus Hannah L. Turkington Stefan Schmutz Osvaldo Zagordi Matthias Lenk Martin Beer Silke Stertz Benjamin G. Hale Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation
description	Polymorphisms in the avian influenza A virus (IAV) polymerase restrict its host range during transmission from birds to mammals. Here, the authors investigate differences in the host chromatin regulator ANP32A regarding IAV polymerase adaptation, and profile ANP32A splicing to predict avian species associated with pre-adaptive human-signatures in the virus.
format	article
author	Patricia Domingues Davide Eletto Carsten Magnus Hannah L. Turkington Stefan Schmutz Osvaldo Zagordi Matthias Lenk Martin Beer Silke Stertz Benjamin G. Hale
author_facet	Patricia Domingues Davide Eletto Carsten Magnus Hannah L. Turkington Stefan Schmutz Osvaldo Zagordi Matthias Lenk Martin Beer Silke Stertz Benjamin G. Hale
author_sort	Patricia Domingues
title	Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation
title_short	Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation
title_full	Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation
title_fullStr	Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation
title_full_unstemmed	Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation
title_sort	profiling host anp32a splicing landscapes to predict influenza a virus polymerase adaptation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c571427377a442969ca7292bcf2a560b
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Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation

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