Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems
ABSTRACT CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems in bacteria and archaea employ CRISPR RNAs to specifically recognize the complementary DNA of foreign invaders, leading to sequence-specific cleavage or degradation of the target DNA. Recent w...
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Main Authors: | Ahmed A. Gomaa, Heidi E. Klumpe, Michelle L. Luo, Kurt Selle, Rodolphe Barrangou, Chase L. Beisel |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2014
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Online Access: | https://doaj.org/article/c576f41a762341faa31fc570780b6d0d |
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