Exploring the binding sites and proton diffusion on insulin amyloid fibril surfaces by naphthol-based photoacid fluorescence and molecular simulations
Abstract The diffusion of protons along biological surfaces and the interaction of biological structures with water are fundamental areas of interest in biology and chemistry. Here, we examine the surface of insulin amyloid fibrils and follow the binding of small molecules (photoacids) that differ a...
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Auteurs principaux: | Nadav Amdursky, M. Harunur Rashid, Molly M. Stevens, Irene Yarovsky |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/c5801a2a11c94967a4c19ccd1dd07ca0 |
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