The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome

The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome

Abstract Neurogenesis impairment is a key determinant of intellectual disability in Down syndrome (DS), a genetic pathology due to triplication of chromosome 21. Since neurogenesis ceases after birth, apart in the hippocampus and olfactory bulb, the only means to tackle the problem of neurogenesis i...

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Autores principales: Fiorenza Stagni, Beatrice Uguagliati, Marco Emili, Andrea Giacomini, Renata Bartesaghi, Sandra Guidi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/c58155709adf40d0a87e2965191ed5f7
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