Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5

Pulmonary fibrosis is a serious disease characterized by extracellular matrix (ECM) component overproduction and remodeling. Insulin-like growth factor-binding protein 5 (IGFBP5) is a conserved member of the IGFBP family of proteins that is overexpressed in fibrotic tissues and promotes fibrosis. We...

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Bibliographic Details
Main Authors: Xinh-Xinh Nguyen, Ludivine Renaud, Carol Feghali-Bostwick
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/c5a6d2ee7b824825a1564a8dc271b74b
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