Prenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age.
The purpose of the study was to determine whether mothers' adversities experienced during early pregnancy are associated with offspring's autonomic nervous system (ANS) reactivity trajectories from 6 months to 5 years of age. This cohort study of primarily Latino families included maternal...
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Public Library of Science (PLoS)
2014
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oai:doaj.org-article:c5a78b348d764b1fabea02cd822eea542021-11-18T08:36:48ZPrenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age.1932-620310.1371/journal.pone.0086283https://doaj.org/article/c5a78b348d764b1fabea02cd822eea542014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24466003/?tool=EBIhttps://doaj.org/toc/1932-6203The purpose of the study was to determine whether mothers' adversities experienced during early pregnancy are associated with offspring's autonomic nervous system (ANS) reactivity trajectories from 6 months to 5 years of age. This cohort study of primarily Latino families included maternal interviews at 13-14 weeks gestation about their experience of a range of adversities: father's absence, general social support, poverty level, and household density. ANS measures of heart rate, respiratory sinus arrhythmia (parasympathetic nervous system) and preejection period (sympathetic nervous system) were collected during resting and challenging conditions on children at 6 months and 1, 3.5 and 5 years of age. Reactivity measures were calculated as the mean of the responses to challenging conditions minus a resting condition. Fixed effects models were conducted for the 212 children with two or more timepoints of ANS measures. Interactions between maternal prenatal adversity levels and child age at time of ANS protocol were included in the models, allowing the calculation of separate trajectories or slopes for each level of adversity. Results showed no significant relations between mothers' prenatal socioeconomic or social support adversity and offspring's parasympathetic nervous system trajectories, but there was a statistically significant relationship between social support adversity and offspring's heart rate trajectories (p<.05) and a borderline significant relationship between socioeconomic adversity and offspring's sympathetic nervous system trajectories (p = .05). Children whose mothers experienced one, not two, social support adversity had the smallest increases in heart rate reactivity compared to children whose mothers experienced no adversity. The children whose mothers experienced no social support and no socioeconomic adversity had the largest increases in heart rate and preejection period respectively from 6 months to 5 years showing the most plasticity. Mothers' prenatal adverse experiences may program their children's physiologic trajectory to dampen their heart rate or sympathetic responsivity to challenging conditions.Abbey AlkonW Thomas BoyceLinh TranKim G HarleyJohn NeuhausBrenda EskenaziPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 1, p e86283 (2014) |
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DOAJ |
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DOAJ |
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EN |
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Medicine R Science Q |
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Medicine R Science Q Abbey Alkon W Thomas Boyce Linh Tran Kim G Harley John Neuhaus Brenda Eskenazi Prenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age. |
| description |
The purpose of the study was to determine whether mothers' adversities experienced during early pregnancy are associated with offspring's autonomic nervous system (ANS) reactivity trajectories from 6 months to 5 years of age. This cohort study of primarily Latino families included maternal interviews at 13-14 weeks gestation about their experience of a range of adversities: father's absence, general social support, poverty level, and household density. ANS measures of heart rate, respiratory sinus arrhythmia (parasympathetic nervous system) and preejection period (sympathetic nervous system) were collected during resting and challenging conditions on children at 6 months and 1, 3.5 and 5 years of age. Reactivity measures were calculated as the mean of the responses to challenging conditions minus a resting condition. Fixed effects models were conducted for the 212 children with two or more timepoints of ANS measures. Interactions between maternal prenatal adversity levels and child age at time of ANS protocol were included in the models, allowing the calculation of separate trajectories or slopes for each level of adversity. Results showed no significant relations between mothers' prenatal socioeconomic or social support adversity and offspring's parasympathetic nervous system trajectories, but there was a statistically significant relationship between social support adversity and offspring's heart rate trajectories (p<.05) and a borderline significant relationship between socioeconomic adversity and offspring's sympathetic nervous system trajectories (p = .05). Children whose mothers experienced one, not two, social support adversity had the smallest increases in heart rate reactivity compared to children whose mothers experienced no adversity. The children whose mothers experienced no social support and no socioeconomic adversity had the largest increases in heart rate and preejection period respectively from 6 months to 5 years showing the most plasticity. Mothers' prenatal adverse experiences may program their children's physiologic trajectory to dampen their heart rate or sympathetic responsivity to challenging conditions. |
| format |
article |
| author |
Abbey Alkon W Thomas Boyce Linh Tran Kim G Harley John Neuhaus Brenda Eskenazi |
| author_facet |
Abbey Alkon W Thomas Boyce Linh Tran Kim G Harley John Neuhaus Brenda Eskenazi |
| author_sort |
Abbey Alkon |
| title |
Prenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age. |
| title_short |
Prenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age. |
| title_full |
Prenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age. |
| title_fullStr |
Prenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age. |
| title_full_unstemmed |
Prenatal adversities and Latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age. |
| title_sort |
prenatal adversities and latino children's autonomic nervous system reactivity trajectories from 6 months to 5 years of age. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2014 |
| url |
https://doaj.org/article/c5a78b348d764b1fabea02cd822eea54 |
| work_keys_str_mv |
AT abbeyalkon prenataladversitiesandlatinochildrensautonomicnervoussystemreactivitytrajectoriesfrom6monthsto5yearsofage AT wthomasboyce prenataladversitiesandlatinochildrensautonomicnervoussystemreactivitytrajectoriesfrom6monthsto5yearsofage AT linhtran prenataladversitiesandlatinochildrensautonomicnervoussystemreactivitytrajectoriesfrom6monthsto5yearsofage AT kimgharley prenataladversitiesandlatinochildrensautonomicnervoussystemreactivitytrajectoriesfrom6monthsto5yearsofage AT johnneuhaus prenataladversitiesandlatinochildrensautonomicnervoussystemreactivitytrajectoriesfrom6monthsto5yearsofage AT brendaeskenazi prenataladversitiesandlatinochildrensautonomicnervoussystemreactivitytrajectoriesfrom6monthsto5yearsofage |
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