Targeting MAGE-C1/CT7 expression increases cell sensitivity to the proteasome inhibitor bortezomib in multiple myeloma cell lines.
The MAGE-C1/CT7 encodes a cancer/testis antigen (CTA), is located on the chromosomal region Xq26-27 and is highly polymorphic in humans. MAGE-C1/CT7 is frequently expressed in multiple myeloma (MM) that may be a potential target for immunotherapy in this still incurable disease. MAGEC1/CT7 expressio...
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Autores principales: | Fabricio de Carvalho, Erico T Costa, Anamaria A Camargo, Juliana C Gregorio, Cibele Masotti, Valeria C C Andrade, Bryan E Strauss, Otavia L Caballero, Djordje Atanackovic, Gisele W B Colleoni |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/c5b75998a15e4ceb80f81b61485aeab2 |
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