Recurrent Strongyloides stercoralis infection in an HIV+ patient
Although infection with Strongyloides stercoralis is often subclinical, some infections persist for decades due to the parasite’s autoinfective lifecycle. Hyperinfection syndrome, however, characterized by a massive increase in parasite burden as a result of host immunosuppression causes a myriad of...
Guardado en:
Autores principales: | , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c5b85c9114984ffa95bbf42536f12b39 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:c5b85c9114984ffa95bbf42536f12b39 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:c5b85c9114984ffa95bbf42536f12b392021-11-04T04:31:08ZRecurrent Strongyloides stercoralis infection in an HIV+ patient2214-250910.1016/j.idcr.2021.e01325https://doaj.org/article/c5b85c9114984ffa95bbf42536f12b392021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S221425092100281Xhttps://doaj.org/toc/2214-2509Although infection with Strongyloides stercoralis is often subclinical, some infections persist for decades due to the parasite’s autoinfective lifecycle. Hyperinfection syndrome, however, characterized by a massive increase in parasite burden as a result of host immunosuppression causes a myriad of clinical symptoms and is associated with high mortality. Use of corticosteroids and infection with HTLV-1 virus are the biggest traditional risk factors for hyperinfection syndrome, though its development can occur with virtually any degree of immunosuppression. Recurrent hyperinfection syndrome, though rare, has also been demonstrated in persons with ongoing immunosuppression, prompting many experts to recommend continued prophylactic treatment in at risk populations. We present the case of a recurrent S. stercoralis hyperinfection occurring four years after previous treatment with anti-helminthic therapy in a patient with AIDS with intermittent adherence to antiretroviral therapy (ART), highlighting diagnostic and treatment issues in the management of recurrent S. stercoralis infection.Kelli BagwellJaya VasudevanKristin MondyElsevierarticleHIVAIDSRecurrent Strongyloides stercoralis hyperinfectionInfectious and parasitic diseasesRC109-216ENIDCases, Vol 26, Iss , Pp e01325- (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
HIV AIDS Recurrent Strongyloides stercoralis hyperinfection Infectious and parasitic diseases RC109-216 |
spellingShingle |
HIV AIDS Recurrent Strongyloides stercoralis hyperinfection Infectious and parasitic diseases RC109-216 Kelli Bagwell Jaya Vasudevan Kristin Mondy Recurrent Strongyloides stercoralis infection in an HIV+ patient |
description |
Although infection with Strongyloides stercoralis is often subclinical, some infections persist for decades due to the parasite’s autoinfective lifecycle. Hyperinfection syndrome, however, characterized by a massive increase in parasite burden as a result of host immunosuppression causes a myriad of clinical symptoms and is associated with high mortality. Use of corticosteroids and infection with HTLV-1 virus are the biggest traditional risk factors for hyperinfection syndrome, though its development can occur with virtually any degree of immunosuppression. Recurrent hyperinfection syndrome, though rare, has also been demonstrated in persons with ongoing immunosuppression, prompting many experts to recommend continued prophylactic treatment in at risk populations. We present the case of a recurrent S. stercoralis hyperinfection occurring four years after previous treatment with anti-helminthic therapy in a patient with AIDS with intermittent adherence to antiretroviral therapy (ART), highlighting diagnostic and treatment issues in the management of recurrent S. stercoralis infection. |
format |
article |
author |
Kelli Bagwell Jaya Vasudevan Kristin Mondy |
author_facet |
Kelli Bagwell Jaya Vasudevan Kristin Mondy |
author_sort |
Kelli Bagwell |
title |
Recurrent Strongyloides stercoralis infection in an HIV+ patient |
title_short |
Recurrent Strongyloides stercoralis infection in an HIV+ patient |
title_full |
Recurrent Strongyloides stercoralis infection in an HIV+ patient |
title_fullStr |
Recurrent Strongyloides stercoralis infection in an HIV+ patient |
title_full_unstemmed |
Recurrent Strongyloides stercoralis infection in an HIV+ patient |
title_sort |
recurrent strongyloides stercoralis infection in an hiv+ patient |
publisher |
Elsevier |
publishDate |
2021 |
url |
https://doaj.org/article/c5b85c9114984ffa95bbf42536f12b39 |
work_keys_str_mv |
AT kellibagwell recurrentstrongyloidesstercoralisinfectioninanhivpatient AT jayavasudevan recurrentstrongyloidesstercoralisinfectioninanhivpatient AT kristinmondy recurrentstrongyloidesstercoralisinfectioninanhivpatient |
_version_ |
1718445300161445888 |