Identical folds used for distinct mechanical functions of the bacterial flagellar rod and hook

The bacterial flagellum is a motile organelle that enables bacterial movement. Here the authors explain how the structurally similar flagellum components FlgG and FlgE can give rise to distinct macrostructures—the rod and hook—through subtle differences in domain orientation attributable to a short...

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Auteurs principaux: Takashi Fujii, Takayuki Kato, Koichi D. Hiraoka, Tomoko Miyata, Tohru Minamino, Fabienne F. V. Chevance, Kelly T. Hughes, Keiichi Namba
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/c5b9b41b0a2d454f8275827ce0b51b2c
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Résumé:The bacterial flagellum is a motile organelle that enables bacterial movement. Here the authors explain how the structurally similar flagellum components FlgG and FlgE can give rise to distinct macrostructures—the rod and hook—through subtle differences in domain orientation attributable to a short N-terminal insertion in FlgG.