Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150

Here, cryo-EM reconstructions of human cytomegalovirus (HCMV) virions reveal host tRNAs associated with the virion’s capsid-bound tegument protein, pp150. tRNA recruitment is mediated by the interactions specific for HCMV only, suggesting the explanation for the absence of such tRNA densities in rel...

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Autores principales:	Yun-Tao Liu, David Strugatsky, Wei Liu, Z. Hong Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c5d1d806596140fe9db2edf92dcac3a6
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spelling	oai:doaj.org-article:c5d1d806596140fe9db2edf92dcac3a62021-12-02T18:50:53ZStructure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp15010.1038/s41467-021-25791-12041-1723https://doaj.org/article/c5d1d806596140fe9db2edf92dcac3a62021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25791-1https://doaj.org/toc/2041-1723Here, cryo-EM reconstructions of human cytomegalovirus (HCMV) virions reveal host tRNAs associated with the virion’s capsid-bound tegument protein, pp150. tRNA recruitment is mediated by the interactions specific for HCMV only, suggesting the explanation for the absence of such tRNA densities in related herpesviruses.Yun-Tao LiuDavid StrugatskyWei LiuZ. Hong ZhouNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yun-Tao Liu David Strugatsky Wei Liu Z. Hong Zhou Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150
description	Here, cryo-EM reconstructions of human cytomegalovirus (HCMV) virions reveal host tRNAs associated with the virion’s capsid-bound tegument protein, pp150. tRNA recruitment is mediated by the interactions specific for HCMV only, suggesting the explanation for the absence of such tRNA densities in related herpesviruses.
format	article
author	Yun-Tao Liu David Strugatsky Wei Liu Z. Hong Zhou
author_facet	Yun-Tao Liu David Strugatsky Wei Liu Z. Hong Zhou
author_sort	Yun-Tao Liu
title	Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150
title_short	Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150
title_full	Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150
title_fullStr	Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150
title_full_unstemmed	Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150
title_sort	structure of human cytomegalovirus virion reveals host trna binding to capsid-associated tegument protein pp150
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c5d1d806596140fe9db2edf92dcac3a6
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Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150

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