Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion

Intoxication with tricyclic antidepressant drugs causes serious toxic findings even at low doses. Despite common use of the antidepressant drugs, there are no randomized controlled trials about treatments in tricyclic antidepressant drug intoxication. Here we report a 23-month-old girl admitted to t...

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Autores principales: Ayyüce Ünlü, Mehmet Alakaya, Sadık Kaya, Ali Ertuğ Arslankoylu, Ali Korulmaz
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Lenguaje:EN
TR
Publicado: Galenos Yayinevi 2021
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Acceso en línea:https://doaj.org/article/c5d34cf72543432aadac809ccd79d44a
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spelling oai:doaj.org-article:c5d34cf72543432aadac809ccd79d44a2021-11-23T10:20:16ZSevere Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion2146-23992148-733210.4274/cayd.galenos.2021.53824https://doaj.org/article/c5d34cf72543432aadac809ccd79d44a2021-12-01T00:00:00Z http://www.caybdergi.com/archives/archive-detail/article-preview/severe-amitriptillin-ntoxication-treated-with-ntra/49683 https://doaj.org/toc/2146-2399https://doaj.org/toc/2148-7332Intoxication with tricyclic antidepressant drugs causes serious toxic findings even at low doses. Despite common use of the antidepressant drugs, there are no randomized controlled trials about treatments in tricyclic antidepressant drug intoxication. Here we report a 23-month-old girl admitted to the emergency room with status epilepticus. We diagnosed that she had ingested toxic amount of amitriptillin. Since the patient’s clinical status deteriorated despite conventional treatments (lidocaine, epinephrine, norepinephrine, magnesium sulphate, sodium bicarbonate, activated charcoal), we administered intravenous lipid emulsion and treated the patient successfully.Ayyüce ÜnlüMehmet AlakayaSadık KayaAli Ertuğ ArslankoyluAli KorulmazGalenos Yayineviarticleintoxicationintravenous lipid emulsionchildMedicineRPediatricsRJ1-570Medical emergencies. Critical care. Intensive care. First aidRC86-88.9ENTRJournal of Pediatric Emergency and Intensive Care Medicine, Vol 8, Iss 3, Pp 185-188 (2021)
institution DOAJ
collection DOAJ
language EN
TR
topic intoxication
intravenous lipid emulsion
child
Medicine
R
Pediatrics
RJ1-570
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
spellingShingle intoxication
intravenous lipid emulsion
child
Medicine
R
Pediatrics
RJ1-570
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Ayyüce Ünlü
Mehmet Alakaya
Sadık Kaya
Ali Ertuğ Arslankoylu
Ali Korulmaz
Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion
description Intoxication with tricyclic antidepressant drugs causes serious toxic findings even at low doses. Despite common use of the antidepressant drugs, there are no randomized controlled trials about treatments in tricyclic antidepressant drug intoxication. Here we report a 23-month-old girl admitted to the emergency room with status epilepticus. We diagnosed that she had ingested toxic amount of amitriptillin. Since the patient’s clinical status deteriorated despite conventional treatments (lidocaine, epinephrine, norepinephrine, magnesium sulphate, sodium bicarbonate, activated charcoal), we administered intravenous lipid emulsion and treated the patient successfully.
format article
author Ayyüce Ünlü
Mehmet Alakaya
Sadık Kaya
Ali Ertuğ Arslankoylu
Ali Korulmaz
author_facet Ayyüce Ünlü
Mehmet Alakaya
Sadık Kaya
Ali Ertuğ Arslankoylu
Ali Korulmaz
author_sort Ayyüce Ünlü
title Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion
title_short Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion
title_full Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion
title_fullStr Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion
title_full_unstemmed Severe Amitriptillin Intoxication Treated with Intravenous Lipid Emulsion
title_sort severe amitriptillin intoxication treated with intravenous lipid emulsion
publisher Galenos Yayinevi
publishDate 2021
url https://doaj.org/article/c5d34cf72543432aadac809ccd79d44a
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AT mehmetalakaya severeamitriptillinintoxicationtreatedwithintravenouslipidemulsion
AT sadıkkaya severeamitriptillinintoxicationtreatedwithintravenouslipidemulsion
AT aliertugarslankoylu severeamitriptillinintoxicationtreatedwithintravenouslipidemulsion
AT alikorulmaz severeamitriptillinintoxicationtreatedwithintravenouslipidemulsion
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