Label-free imaging for quality control of cardiomyocyte differentiation

Differentiation of hPSCs to cardiomyocytes suffers from high variability. Here the authors report a label-free live cell imaging platform based on autofluorescence imaging to enable the prediction of cardiomyocyte differentiation efficiency from hPSCs.

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Autores principales: Tongcheng Qian, Tiffany M. Heaster, Angela R. Houghtaling, Kexin Sun, Kayvan Samimi, Melissa C. Skala
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c5d52f0785354812a3fc8a57e5918298
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spelling oai:doaj.org-article:c5d52f0785354812a3fc8a57e59182982021-12-02T16:30:15ZLabel-free imaging for quality control of cardiomyocyte differentiation10.1038/s41467-021-24868-12041-1723https://doaj.org/article/c5d52f0785354812a3fc8a57e59182982021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24868-1https://doaj.org/toc/2041-1723Differentiation of hPSCs to cardiomyocytes suffers from high variability. Here the authors report a label-free live cell imaging platform based on autofluorescence imaging to enable the prediction of cardiomyocyte differentiation efficiency from hPSCs.Tongcheng QianTiffany M. HeasterAngela R. HoughtalingKexin SunKayvan SamimiMelissa C. SkalaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tongcheng Qian
Tiffany M. Heaster
Angela R. Houghtaling
Kexin Sun
Kayvan Samimi
Melissa C. Skala
Label-free imaging for quality control of cardiomyocyte differentiation
description Differentiation of hPSCs to cardiomyocytes suffers from high variability. Here the authors report a label-free live cell imaging platform based on autofluorescence imaging to enable the prediction of cardiomyocyte differentiation efficiency from hPSCs.
format article
author Tongcheng Qian
Tiffany M. Heaster
Angela R. Houghtaling
Kexin Sun
Kayvan Samimi
Melissa C. Skala
author_facet Tongcheng Qian
Tiffany M. Heaster
Angela R. Houghtaling
Kexin Sun
Kayvan Samimi
Melissa C. Skala
author_sort Tongcheng Qian
title Label-free imaging for quality control of cardiomyocyte differentiation
title_short Label-free imaging for quality control of cardiomyocyte differentiation
title_full Label-free imaging for quality control of cardiomyocyte differentiation
title_fullStr Label-free imaging for quality control of cardiomyocyte differentiation
title_full_unstemmed Label-free imaging for quality control of cardiomyocyte differentiation
title_sort label-free imaging for quality control of cardiomyocyte differentiation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c5d52f0785354812a3fc8a57e5918298
work_keys_str_mv AT tongchengqian labelfreeimagingforqualitycontrolofcardiomyocytedifferentiation
AT tiffanymheaster labelfreeimagingforqualitycontrolofcardiomyocytedifferentiation
AT angelarhoughtaling labelfreeimagingforqualitycontrolofcardiomyocytedifferentiation
AT kexinsun labelfreeimagingforqualitycontrolofcardiomyocytedifferentiation
AT kayvansamimi labelfreeimagingforqualitycontrolofcardiomyocytedifferentiation
AT melissacskala labelfreeimagingforqualitycontrolofcardiomyocytedifferentiation
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