Applications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals

Deep eutectic solvents are liquid mixtures of solid components at room temperature, which present exceptional properties: high solvent capacity, high biodegradation, low volatile organic compound character, and relatively low toxicity. Furthermore, there are an important number of DES described, for...

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Autores principales: Laura Lomba, Cristina B. García, Mª Pilar Ribate, Beatriz Giner, Estefanía Zuriaga
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/c5d6c5b44f9040f1a467a1f04ebdbddf
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spelling oai:doaj.org-article:c5d6c5b44f9040f1a467a1f04ebdbddf2021-11-11T15:13:14ZApplications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals10.3390/app1121101562076-3417https://doaj.org/article/c5d6c5b44f9040f1a467a1f04ebdbddf2021-10-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/21/10156https://doaj.org/toc/2076-3417Deep eutectic solvents are liquid mixtures of solid components at room temperature, which present exceptional properties: high solvent capacity, high biodegradation, low volatile organic compound character, and relatively low toxicity. Furthermore, there are an important number of DES described, formed by different components and ratios, and thus, the studied applications are also numerous. In this review, we focused on the applications related to health. One of the most promising applications of DES is the development of oral liquid formulations of poorly soluble active pharmaceutical ingredients, although it currently remains at an early stage. We have analyzed the potential and limitations of DES with this regard. Furthermore, DES have been used as synthesis media. In this work, we revised the use of DES to obtain bioactive natural products via synthesis or extraction process. Finally, the usefulness of DES in other interesting applications for promoting health has been also examined: this is the case of genomics studies, nano-carriers for the encapsulation of anticancer drugs or stabilization of samples for medical purposes.Laura LombaCristina B. GarcíaMª Pilar RibateBeatriz GinerEstefanía ZuriagaMDPI AGarticleDESNADESdeep eutectic solventapplicationsnatural compoundsTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 10156, p 10156 (2021)
institution DOAJ
collection DOAJ
language EN
topic DES
NADES
deep eutectic solvent
applications
natural compounds
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
spellingShingle DES
NADES
deep eutectic solvent
applications
natural compounds
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
Laura Lomba
Cristina B. García
Mª Pilar Ribate
Beatriz Giner
Estefanía Zuriaga
Applications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals
description Deep eutectic solvents are liquid mixtures of solid components at room temperature, which present exceptional properties: high solvent capacity, high biodegradation, low volatile organic compound character, and relatively low toxicity. Furthermore, there are an important number of DES described, formed by different components and ratios, and thus, the studied applications are also numerous. In this review, we focused on the applications related to health. One of the most promising applications of DES is the development of oral liquid formulations of poorly soluble active pharmaceutical ingredients, although it currently remains at an early stage. We have analyzed the potential and limitations of DES with this regard. Furthermore, DES have been used as synthesis media. In this work, we revised the use of DES to obtain bioactive natural products via synthesis or extraction process. Finally, the usefulness of DES in other interesting applications for promoting health has been also examined: this is the case of genomics studies, nano-carriers for the encapsulation of anticancer drugs or stabilization of samples for medical purposes.
format article
author Laura Lomba
Cristina B. García
Mª Pilar Ribate
Beatriz Giner
Estefanía Zuriaga
author_facet Laura Lomba
Cristina B. García
Mª Pilar Ribate
Beatriz Giner
Estefanía Zuriaga
author_sort Laura Lomba
title Applications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals
title_short Applications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals
title_full Applications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals
title_fullStr Applications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals
title_full_unstemmed Applications of Deep Eutectic Solvents Related to Health, Synthesis, and Extraction of Natural Based Chemicals
title_sort applications of deep eutectic solvents related to health, synthesis, and extraction of natural based chemicals
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/c5d6c5b44f9040f1a467a1f04ebdbddf
work_keys_str_mv AT lauralomba applicationsofdeepeutecticsolventsrelatedtohealthsynthesisandextractionofnaturalbasedchemicals
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AT beatrizginer applicationsofdeepeutecticsolventsrelatedtohealthsynthesisandextractionofnaturalbasedchemicals
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