LineageOT is a unified framework for lineage tracing and trajectory inference

Lineage tracing and snapshots of transcriptional state at the single-cell level are powerful, complementary tools for studying development. Here, the authors propose a mathematical method combining lineage tracing with trajectory inference to improve our understanding of development.

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Autores principales: Aden Forrow, Geoffrey Schiebinger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c5d6e1f958ee48a982453998f82cc8ac
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spelling oai:doaj.org-article:c5d6e1f958ee48a982453998f82cc8ac2021-12-02T18:01:13ZLineageOT is a unified framework for lineage tracing and trajectory inference10.1038/s41467-021-25133-12041-1723https://doaj.org/article/c5d6e1f958ee48a982453998f82cc8ac2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25133-1https://doaj.org/toc/2041-1723Lineage tracing and snapshots of transcriptional state at the single-cell level are powerful, complementary tools for studying development. Here, the authors propose a mathematical method combining lineage tracing with trajectory inference to improve our understanding of development.Aden ForrowGeoffrey SchiebingerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aden Forrow
Geoffrey Schiebinger
LineageOT is a unified framework for lineage tracing and trajectory inference
description Lineage tracing and snapshots of transcriptional state at the single-cell level are powerful, complementary tools for studying development. Here, the authors propose a mathematical method combining lineage tracing with trajectory inference to improve our understanding of development.
format article
author Aden Forrow
Geoffrey Schiebinger
author_facet Aden Forrow
Geoffrey Schiebinger
author_sort Aden Forrow
title LineageOT is a unified framework for lineage tracing and trajectory inference
title_short LineageOT is a unified framework for lineage tracing and trajectory inference
title_full LineageOT is a unified framework for lineage tracing and trajectory inference
title_fullStr LineageOT is a unified framework for lineage tracing and trajectory inference
title_full_unstemmed LineageOT is a unified framework for lineage tracing and trajectory inference
title_sort lineageot is a unified framework for lineage tracing and trajectory inference
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c5d6e1f958ee48a982453998f82cc8ac
work_keys_str_mv AT adenforrow lineageotisaunifiedframeworkforlineagetracingandtrajectoryinference
AT geoffreyschiebinger lineageotisaunifiedframeworkforlineagetracingandtrajectoryinference
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