Tumor-selective catalytic nanomedicine by nanocatalyst delivery

The specific metabolism of cancer cells may allow for selective tumor therapeutics. Here, the authors show that a suitable combination of an enzyme and iron nanoparticles loaded on dendritic silica induces apoptosis of cancer cells in response to the glucose-reliant and mild acidic microenvironment.

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Detalles Bibliográficos
Autores principales:	Minfeng Huo, Liying Wang, Yu Chen, Jianlin Shi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c5d8207be121418abae075316c2f8030
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spelling	oai:doaj.org-article:c5d8207be121418abae075316c2f80302021-12-02T15:38:51ZTumor-selective catalytic nanomedicine by nanocatalyst delivery10.1038/s41467-017-00424-82041-1723https://doaj.org/article/c5d8207be121418abae075316c2f80302017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00424-8https://doaj.org/toc/2041-1723The specific metabolism of cancer cells may allow for selective tumor therapeutics. Here, the authors show that a suitable combination of an enzyme and iron nanoparticles loaded on dendritic silica induces apoptosis of cancer cells in response to the glucose-reliant and mild acidic microenvironment.Minfeng HuoLiying WangYu ChenJianlin ShiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Minfeng Huo Liying Wang Yu Chen Jianlin Shi Tumor-selective catalytic nanomedicine by nanocatalyst delivery
description	The specific metabolism of cancer cells may allow for selective tumor therapeutics. Here, the authors show that a suitable combination of an enzyme and iron nanoparticles loaded on dendritic silica induces apoptosis of cancer cells in response to the glucose-reliant and mild acidic microenvironment.
format	article
author	Minfeng Huo Liying Wang Yu Chen Jianlin Shi
author_facet	Minfeng Huo Liying Wang Yu Chen Jianlin Shi
author_sort	Minfeng Huo
title	Tumor-selective catalytic nanomedicine by nanocatalyst delivery
title_short	Tumor-selective catalytic nanomedicine by nanocatalyst delivery
title_full	Tumor-selective catalytic nanomedicine by nanocatalyst delivery
title_fullStr	Tumor-selective catalytic nanomedicine by nanocatalyst delivery
title_full_unstemmed	Tumor-selective catalytic nanomedicine by nanocatalyst delivery
title_sort	tumor-selective catalytic nanomedicine by nanocatalyst delivery
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/c5d8207be121418abae075316c2f8030
work_keys_str_mv	AT minfenghuo tumorselectivecatalyticnanomedicinebynanocatalystdelivery AT liyingwang tumorselectivecatalyticnanomedicinebynanocatalystdelivery AT yuchen tumorselectivecatalyticnanomedicinebynanocatalystdelivery AT jianlinshi tumorselectivecatalyticnanomedicinebynanocatalystdelivery
_version_	1718386073447432192

Tumor-selective catalytic nanomedicine by nanocatalyst delivery

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