Streptococcus pneumoniae Interacts with pIgR expressed by the brain microvascular endothelium but does not co-localize with PAF receptor.
Streptococcus pneumoniae is thought to adhere to the blood-brain barrier (BBB) endothelium prior to causing meningitis. The platelet activating factor receptor (PAFR) has been implicated in this adhesion but there is a paucity of data demonstrating direct binding of the bacteria to PAFR. Additionall...
Saved in:
Main Authors: | Federico Iovino, Grietje Molema, Jetta J E Bijlsma |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
|
Subjects: | |
Online Access: | https://doaj.org/article/c5d8716b16014dc98c1f11d6f6d799b5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Proteasome-Ubiquitin System Is Required for Efficient Killing of Intracellular <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> by Brain Endothelial Cells
by: Federico Iovino, et al.
Published: (2014) -
Streptococcus pneumoniae invades endothelial host cells via multiple pathways and is killed in a lysosome dependent manner.
by: Henrik Gradstedt, et al.
Published: (2013) -
The brain microvascular endothelium supports T cell proliferation and has potential for alloantigen presentation.
by: Julie Wheway, et al.
Published: (2013) -
Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease
by: Zhiming Wang, et al.
Published: (2020) -
All muscarinic acetylcholine receptors (M1-M5) are expressed in murine brain microvascular endothelium
by: Beatrice Mihaela Radu, et al.
Published: (2017)