The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea

Abstract Objective Obstructive sleep apnoea (OSA) is one cause of pulmonary hypertension (PH) and can also emerge along with PH. The clinical diagnosis and treatment of OSA in patients with PH are still controversial. The purpose of this clinical observation study was to observe and summarize the in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lu Yan, Zhihui Zhao, Qing Zhao, Qi Jin, Yi Zhang, Xin Li, Anqi Duan, Qin Luo, Zhihong Liu
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Pulmonary hypertension Obstructive sleep apnoea Risk factors Diseases of the respiratory system RC705-779
Acceso en línea:	https://doaj.org/article/c5f32cac27384f3b9bca6616940f4c58
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c5f32cac27384f3b9bca6616940f4c58
record_format	dspace
spelling	oai:doaj.org-article:c5f32cac27384f3b9bca6616940f4c582021-11-28T12:36:31ZThe clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea10.1186/s12890-021-01755-51471-2466https://doaj.org/article/c5f32cac27384f3b9bca6616940f4c582021-11-01T00:00:00Zhttps://doi.org/10.1186/s12890-021-01755-5https://doaj.org/toc/1471-2466Abstract Objective Obstructive sleep apnoea (OSA) is one cause of pulmonary hypertension (PH) and can also emerge along with PH. The clinical diagnosis and treatment of OSA in patients with PH are still controversial. The purpose of this clinical observation study was to observe and summarize the incidence and clinical characteristics of OSA in patients with PH and to explore possible predictors of PH combined with OSA. Methods Patients with PH diagnosed by right heart catheterization who underwent overnight cardiorespiratory monitoring from December 2018 to December 2020 were enrolled. OSA was defined as an apnoea–hypopnoea index of ≥ 5/h with ≥ 50% of apnoeic events being obstructive. Baseline clinical characteristics and parameters were collected to compare PH patients with and without OSA. Logistic regression analysis was run to determine the risk factors for OSA in PH patients. Results A total of 35 (25%) of 140 patients had OSA. OSA is relatively frequent in patients with PH, especially in patients with chronic thromboembolic pulmonary hypertension and patients with lung disease– or hypoxia-associated PH. The patients who had OSA were mostly male and had a higher age and a lower daytime arterial oxygen pressure. Logistic regression analysis found that older age, male sex, and lower daytime arterial blood oxygen pressure correlated with OSA in PH patients. Conclusion OSA is common in patients with PH. Lower daytime arterial oxygen pressure is a risk factor for OSA in older male patients with PH.Lu YanZhihui ZhaoQing ZhaoQi JinYi ZhangXin LiAnqi DuanQin LuoZhihong LiuBMCarticlePulmonary hypertensionObstructive sleep apnoeaRisk factorsDiseases of the respiratory systemRC705-779ENBMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pulmonary hypertension Obstructive sleep apnoea Risk factors Diseases of the respiratory system RC705-779
spellingShingle	Pulmonary hypertension Obstructive sleep apnoea Risk factors Diseases of the respiratory system RC705-779 Lu Yan Zhihui Zhao Qing Zhao Qi Jin Yi Zhang Xin Li Anqi Duan Qin Luo Zhihong Liu The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea
description	Abstract Objective Obstructive sleep apnoea (OSA) is one cause of pulmonary hypertension (PH) and can also emerge along with PH. The clinical diagnosis and treatment of OSA in patients with PH are still controversial. The purpose of this clinical observation study was to observe and summarize the incidence and clinical characteristics of OSA in patients with PH and to explore possible predictors of PH combined with OSA. Methods Patients with PH diagnosed by right heart catheterization who underwent overnight cardiorespiratory monitoring from December 2018 to December 2020 were enrolled. OSA was defined as an apnoea–hypopnoea index of ≥ 5/h with ≥ 50% of apnoeic events being obstructive. Baseline clinical characteristics and parameters were collected to compare PH patients with and without OSA. Logistic regression analysis was run to determine the risk factors for OSA in PH patients. Results A total of 35 (25%) of 140 patients had OSA. OSA is relatively frequent in patients with PH, especially in patients with chronic thromboembolic pulmonary hypertension and patients with lung disease– or hypoxia-associated PH. The patients who had OSA were mostly male and had a higher age and a lower daytime arterial oxygen pressure. Logistic regression analysis found that older age, male sex, and lower daytime arterial blood oxygen pressure correlated with OSA in PH patients. Conclusion OSA is common in patients with PH. Lower daytime arterial oxygen pressure is a risk factor for OSA in older male patients with PH.
format	article
author	Lu Yan Zhihui Zhao Qing Zhao Qi Jin Yi Zhang Xin Li Anqi Duan Qin Luo Zhihong Liu
author_facet	Lu Yan Zhihui Zhao Qing Zhao Qi Jin Yi Zhang Xin Li Anqi Duan Qin Luo Zhihong Liu
author_sort	Lu Yan
title	The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea
title_short	The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea
title_full	The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea
title_fullStr	The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea
title_full_unstemmed	The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea
title_sort	clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea
publisher	BMC
publishDate	2021
url	https://doaj.org/article/c5f32cac27384f3b9bca6616940f4c58
work_keys_str_mv	AT luyan theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT zhihuizhao theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT qingzhao theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT qijin theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT yizhang theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT xinli theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT anqiduan theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT qinluo theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT zhihongliu theclinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT luyan clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT zhihuizhao clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT qingzhao clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT qijin clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT yizhang clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT xinli clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT anqiduan clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT qinluo clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea AT zhihongliu clinicalcharacteristicsofpatientswithpulmonaryhypertensioncombinedwithobstructivesleepapnoea
_version_	1718407919064580096

The clinical characteristics of patients with pulmonary hypertension combined with obstructive sleep apnoea

Ejemplares similares