Human motor neurons generated from neural stem cells delay clinical onset and prolong life in ALS mouse model.
Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease. The etiology and pathogenic mechanisms of the disease remain unknown, and there is no effective treatment. Here we show that intrathecal transplantation of human motor neurons derived from neural stem cells (NSC...
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Autores principales: | Hong J Lee, Kwang S Kim, Jin Ahn, Hye M Bae, Inja Lim, Seung U Kim |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/c5f75793a09a4083aafba55850da6c87 |
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