Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy.
Natural Killer (NK) cells are innate immune cells that secrete lytic granules to directly kill virus-infected or transformed cells across an immune synapse. However, a major gap in understanding this process is in establishing how lytic granules pass through the mesh of cortical actin known to under...
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Autores principales: | Alice C N Brown, Stephane Oddos, Ian M Dobbie, Juha-Matti Alakoskela, Richard M Parton, Philipp Eissmann, Mark A A Neil, Christopher Dunsby, Paul M W French, Ilan Davis, Daniel M Davis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/c5fbcad5246744319db3103246e810fc |
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