High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Single cell RNA sequencing generates short reads from one end of a template, providing incomplete transcript coverage and limiting identification of diverse sequences such as antigen receptors. Here the authors combine long read nanopore sequencing with short read profiling of barcoded libraries to...

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Bibliographic Details
Main Authors: Mandeep Singh, Ghamdan Al-Eryani, Shaun Carswell, James M. Ferguson, James Blackburn, Kirston Barton, Daniel Roden, Fabio Luciani, Tri Giang Phan, Simon Junankar, Katherine Jackson, Christopher C. Goodnow, Martin A. Smith, Alexander Swarbrick
Format: article
Language:EN
Published: Nature Portfolio 2019
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Q
Online Access:https://doaj.org/article/c60a66377d0242a7a325fe287cec34d3
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