A conserved enhancer regulates Il9 expression in multiple lineages

A conserved enhancer regulates Il9 expression in multiple lineages

Interleukin-9 (IL-9) is important for allergy, autoimmunity and tumor immunity, but how its expression is regulated is unclear. Here the authors show the essential function of an enhancer, CNS-25 in mouse and CNS-18 in human, for IL-9 expression, with the deletion of this enhancer severely hampering...

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Autores principales: Byunghee Koh, Amina Abdul Qayum, Rajneesh Srivastava, Yongyao Fu, Benjamin J. Ulrich, Sarath Chandra Janga, Mark H. Kaplan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/c61519e680244108827ba600002853d5
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