Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial

Reliever inhaler overuse and delay in medical review in asthma In asthma, overuse of beta-agonist reliever medication and delay in seeking medical review in an exacerbation are linked to asthma deaths. Janine Pilcher at the Medical Research Institute of New Zealand, and co-workers, conducted a revie...

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Autores principales: Janine Pilcher, Mitesh Patel, Alison Pritchard, Darmiga Thayabaran, Stefan Ebmeier, Dominick Shaw, Peter Black, Irene Braithwaite, Mark Weatherall, Richard Beasley
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c61a595ab85b4f22a0bae3704b80e50f
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spelling oai:doaj.org-article:c61a595ab85b4f22a0bae3704b80e50f2021-12-02T15:18:51ZBeta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial10.1038/s41533-017-0032-z2055-1010https://doaj.org/article/c61a595ab85b4f22a0bae3704b80e50f2017-05-01T00:00:00Zhttps://doi.org/10.1038/s41533-017-0032-zhttps://doaj.org/toc/2055-1010Reliever inhaler overuse and delay in medical review in asthma In asthma, overuse of beta-agonist reliever medication and delay in seeking medical review in an exacerbation are linked to asthma deaths. Janine Pilcher at the Medical Research Institute of New Zealand, and co-workers, conducted a review of data from a study of 303 adult patients with severe asthma, followed over 24 weeks. The patients were allocated to either a budesonide/formoterol, or a salbutamol inhaler to take for symptom relief, in addition to their maintenance treatment. Inhalers were fitted with electronic monitors, to accurately document every use. In both groups, on 90% of days when an exacerbation requiring excess use of an inhaler occurred, patients did not follow-up with medical professionals within 48 h as advised. Further, in both groups, ‘extreme’ reliever inhaler use was recorded at least once in around one in four patients.Janine PilcherMitesh PatelAlison PritchardDarmiga ThayabaranStefan EbmeierDominick ShawPeter BlackIrene BraithwaiteMark WeatherallRichard BeasleyNature PortfolioarticleDiseases of the respiratory systemRC705-779ENnpj Primary Care Respiratory Medicine, Vol 27, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the respiratory system
RC705-779
spellingShingle Diseases of the respiratory system
RC705-779
Janine Pilcher
Mitesh Patel
Alison Pritchard
Darmiga Thayabaran
Stefan Ebmeier
Dominick Shaw
Peter Black
Irene Braithwaite
Mark Weatherall
Richard Beasley
Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
description Reliever inhaler overuse and delay in medical review in asthma In asthma, overuse of beta-agonist reliever medication and delay in seeking medical review in an exacerbation are linked to asthma deaths. Janine Pilcher at the Medical Research Institute of New Zealand, and co-workers, conducted a review of data from a study of 303 adult patients with severe asthma, followed over 24 weeks. The patients were allocated to either a budesonide/formoterol, or a salbutamol inhaler to take for symptom relief, in addition to their maintenance treatment. Inhalers were fitted with electronic monitors, to accurately document every use. In both groups, on 90% of days when an exacerbation requiring excess use of an inhaler occurred, patients did not follow-up with medical professionals within 48 h as advised. Further, in both groups, ‘extreme’ reliever inhaler use was recorded at least once in around one in four patients.
format article
author Janine Pilcher
Mitesh Patel
Alison Pritchard
Darmiga Thayabaran
Stefan Ebmeier
Dominick Shaw
Peter Black
Irene Braithwaite
Mark Weatherall
Richard Beasley
author_facet Janine Pilcher
Mitesh Patel
Alison Pritchard
Darmiga Thayabaran
Stefan Ebmeier
Dominick Shaw
Peter Black
Irene Braithwaite
Mark Weatherall
Richard Beasley
author_sort Janine Pilcher
title Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
title_short Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
title_full Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
title_fullStr Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
title_full_unstemmed Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
title_sort beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c61a595ab85b4f22a0bae3704b80e50f
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