Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial
Reliever inhaler overuse and delay in medical review in asthma In asthma, overuse of beta-agonist reliever medication and delay in seeking medical review in an exacerbation are linked to asthma deaths. Janine Pilcher at the Medical Research Institute of New Zealand, and co-workers, conducted a revie...
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Nature Portfolio
2017
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oai:doaj.org-article:c61a595ab85b4f22a0bae3704b80e50f2021-12-02T15:18:51ZBeta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial10.1038/s41533-017-0032-z2055-1010https://doaj.org/article/c61a595ab85b4f22a0bae3704b80e50f2017-05-01T00:00:00Zhttps://doi.org/10.1038/s41533-017-0032-zhttps://doaj.org/toc/2055-1010Reliever inhaler overuse and delay in medical review in asthma In asthma, overuse of beta-agonist reliever medication and delay in seeking medical review in an exacerbation are linked to asthma deaths. Janine Pilcher at the Medical Research Institute of New Zealand, and co-workers, conducted a review of data from a study of 303 adult patients with severe asthma, followed over 24 weeks. The patients were allocated to either a budesonide/formoterol, or a salbutamol inhaler to take for symptom relief, in addition to their maintenance treatment. Inhalers were fitted with electronic monitors, to accurately document every use. In both groups, on 90% of days when an exacerbation requiring excess use of an inhaler occurred, patients did not follow-up with medical professionals within 48 h as advised. Further, in both groups, ‘extreme’ reliever inhaler use was recorded at least once in around one in four patients.Janine PilcherMitesh PatelAlison PritchardDarmiga ThayabaranStefan EbmeierDominick ShawPeter BlackIrene BraithwaiteMark WeatherallRichard BeasleyNature PortfolioarticleDiseases of the respiratory systemRC705-779ENnpj Primary Care Respiratory Medicine, Vol 27, Iss 1, Pp 1-8 (2017) |
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Diseases of the respiratory system RC705-779 |
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Diseases of the respiratory system RC705-779 Janine Pilcher Mitesh Patel Alison Pritchard Darmiga Thayabaran Stefan Ebmeier Dominick Shaw Peter Black Irene Braithwaite Mark Weatherall Richard Beasley Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial |
description |
Reliever inhaler overuse and delay in medical review in asthma In asthma, overuse of beta-agonist reliever medication and delay in seeking medical review in an exacerbation are linked to asthma deaths. Janine Pilcher at the Medical Research Institute of New Zealand, and co-workers, conducted a review of data from a study of 303 adult patients with severe asthma, followed over 24 weeks. The patients were allocated to either a budesonide/formoterol, or a salbutamol inhaler to take for symptom relief, in addition to their maintenance treatment. Inhalers were fitted with electronic monitors, to accurately document every use. In both groups, on 90% of days when an exacerbation requiring excess use of an inhaler occurred, patients did not follow-up with medical professionals within 48 h as advised. Further, in both groups, ‘extreme’ reliever inhaler use was recorded at least once in around one in four patients. |
format |
article |
author |
Janine Pilcher Mitesh Patel Alison Pritchard Darmiga Thayabaran Stefan Ebmeier Dominick Shaw Peter Black Irene Braithwaite Mark Weatherall Richard Beasley |
author_facet |
Janine Pilcher Mitesh Patel Alison Pritchard Darmiga Thayabaran Stefan Ebmeier Dominick Shaw Peter Black Irene Braithwaite Mark Weatherall Richard Beasley |
author_sort |
Janine Pilcher |
title |
Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial |
title_short |
Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial |
title_full |
Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial |
title_fullStr |
Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial |
title_full_unstemmed |
Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial |
title_sort |
beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c61a595ab85b4f22a0bae3704b80e50f |
work_keys_str_mv |
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