Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription

Histone H3K4 methylation affects gene transcription from yeast to humans. Here, the authors show that Set1 and Jhd2, the only H3K4 methyltransferase and H3K4 demethylase, respectively, in budding yeast, co-regulate both positive and negative transcription mediated by nucleosomal turnover and occupan...

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Autores principales: Saravanan Ramakrishnan, Srijana Pokhrel, Sowmiya Palani, Christian Pflueger, Timothy J. Parnell, Bradley R. Cairns, Srividya Bhaskara, Mahesh B. Chandrasekharan
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c625e8ba26fc4e15b485691b7990fe44
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spelling oai:doaj.org-article:c625e8ba26fc4e15b485691b7990fe442021-12-02T14:40:15ZCounteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription10.1038/ncomms119492041-1723https://doaj.org/article/c625e8ba26fc4e15b485691b7990fe442016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11949https://doaj.org/toc/2041-1723Histone H3K4 methylation affects gene transcription from yeast to humans. Here, the authors show that Set1 and Jhd2, the only H3K4 methyltransferase and H3K4 demethylase, respectively, in budding yeast, co-regulate both positive and negative transcription mediated by nucleosomal turnover and occupancy.Saravanan RamakrishnanSrijana PokhrelSowmiya PalaniChristian PfluegerTimothy J. ParnellBradley R. CairnsSrividya BhaskaraMahesh B. ChandrasekharanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Saravanan Ramakrishnan
Srijana Pokhrel
Sowmiya Palani
Christian Pflueger
Timothy J. Parnell
Bradley R. Cairns
Srividya Bhaskara
Mahesh B. Chandrasekharan
Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
description Histone H3K4 methylation affects gene transcription from yeast to humans. Here, the authors show that Set1 and Jhd2, the only H3K4 methyltransferase and H3K4 demethylase, respectively, in budding yeast, co-regulate both positive and negative transcription mediated by nucleosomal turnover and occupancy.
format article
author Saravanan Ramakrishnan
Srijana Pokhrel
Sowmiya Palani
Christian Pflueger
Timothy J. Parnell
Bradley R. Cairns
Srividya Bhaskara
Mahesh B. Chandrasekharan
author_facet Saravanan Ramakrishnan
Srijana Pokhrel
Sowmiya Palani
Christian Pflueger
Timothy J. Parnell
Bradley R. Cairns
Srividya Bhaskara
Mahesh B. Chandrasekharan
author_sort Saravanan Ramakrishnan
title Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
title_short Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
title_full Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
title_fullStr Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
title_full_unstemmed Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
title_sort counteracting h3k4 methylation modulators set1 and jhd2 co-regulate chromatin dynamics and gene transcription
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/c625e8ba26fc4e15b485691b7990fe44
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